Interlab comparison study with japanese quails for testing the avian acute toxicity of tri-buthyltln oxide (TBTO)

Report of the SETAC/OECD Workshop on Avian Toxicity Testing

“…This feature could be seen as an advantage for the sake of realism, but it presents serious practical problems in a standard test protocol. The Japanese quail reaches peak production after only 2-3 weeks and maintains this production at least for the following 6-8 weeks (Solecki et al 1992(Solecki et al , 1994. Therefore, with the mallard and bobwhite quail there are greater limitations on the ability to use pre-dosing performance of individual birds to compare with chemical effects on egg laying, fertility, hatchability, etc.…”