Interleukin 15 and granulocytes colony stimulating factor levels in relation to ICSI outcome in subfertile PCOS women

Jaddoa, Zainab Obaid; Khalil, Najah Shakir Al; Abbas, Ahmed A.

doi:10.26452/ijrps.v10i3.1389

ijrps

2019

DOI: 10.26452/ijrps.v10i3.1389

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Interleukin 15 and granulocytes colony stimulating factor levels in relation to ICSI outcome in subfertile PCOS women

Zainab Obaid Jaddoa¹,

Najah Shakir Al Khalil²,

Ahmed A. Abbas³

Abstract: Polycystic Ovary Syndrome constitutes a complex heterogeneous disorder, considered one of the leading cause of delayed conception in women. Serum and follicular luid cytokines are subject of extensive studies to identify their role in subfertility with controversial results. This study was aimed to evaluate the relation of Granulocytes Colony Stimulating Factor (G-CSF) and Interleukin 15 (IL 15) levels to ovarian response and ICSI outcome in PCOS women undergoing ICSI. Ovarian hormonal stimulation conducted ac… Show more

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2022

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Cited by 1 publication

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Molecular signature of immunological mechanism behind impaired endometrial receptivity in polycystic ovarian syndrome

Amjadi¹,

Zandieh²,

Mehdizadeh³

et al. 2022

Archives of Endocrinology and Metabolism

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Objective: Despite the treatment of anovulation, infertility is still one of the main complications in PCOS women during reproductive age, which appears to be mainly due to impaired uterine receptivity. This study investigated the transcriptome profiles of endometrium in PCOS patients and healthy fertile individuals as the control group. Material and methods: Total mRNA was extracted from endometrial tissues of PCOS patients (n = 12) and healthy fertile individuals (n = 10) during the luteal phase. After cDNA synthesis, PCR array was performed using Human Female Infertility RT² Profiler PCR Array kit (Qiagen, Cat.No: PAHS-164Z) for evaluating expression of 84 genes contributing to the female infertility. Results: PCR Array data analysis identified significantly greater expression of CSF,

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Molecular signature of immunological mechanism behind impaired endometrial receptivity in polycystic ovarian syndrome

Amjadi¹,

Zandieh²,

Mehdizadeh³

et al. 2022

Archives of Endocrinology and Metabolism

View full text Add to dashboard Cite

show abstract

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Interleukin 15 and granulocytes colony stimulating factor levels in relation to ICSI outcome in subfertile PCOS women

Cited by 1 publication

References 22 publications

Molecular signature of immunological mechanism behind impaired endometrial receptivity in polycystic ovarian syndrome

Molecular signature of immunological mechanism behind impaired endometrial receptivity in polycystic ovarian syndrome

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