Interleukin-6 and Interleukin-8 Levels in Children with Aplastic Anemia and its Correlation with Disease Severity and Response to Immunosuppressive Therapy
Abstract:Background:
Aplastic anemia (AA) is an uncommon condition characterized by pancytopenia and hypocellular bone marrow. Interleukin (IL)-6 and IL-8 have been shown to inhibit myelopoiesis and are major mediators of tissue damage. The primary goal of this study was to determine the IL-6 and IL-8 levels in children with AA, as well as their relationship to illness severity and immunosuppressive medication response.
Materials and Methods:
The IL-6 and IL-8 l… Show more
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