2013
DOI: 10.1016/j.healun.2012.11.023
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Intermediate-term outcomes after combined heart–liver transplantation in children with a univentricular heart

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Cited by 47 publications
(39 citation statements)
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“…[141][142][143][144][145][146] Heart and liver transplantation has been reported in carefully selected patients with Fontan physiology. 147 Preventive strategies include confirmation of hepatitis B immunity in patients who have undergone vaccination previously and immunization for hepatitis A and B for those who are not currently immune. Any patients found to be chronically infected with hepatitis C are referred for possible antiviral therapy.…”
Section: Managementmentioning
confidence: 99%
“…[141][142][143][144][145][146] Heart and liver transplantation has been reported in carefully selected patients with Fontan physiology. 147 Preventive strategies include confirmation of hepatitis B immunity in patients who have undergone vaccination previously and immunization for hepatitis A and B for those who are not currently immune. Any patients found to be chronically infected with hepatitis C are referred for possible antiviral therapy.…”
Section: Managementmentioning
confidence: 99%
“…Cases of successful combined heart-liver transplantation in pediatric and adult CHD have been reported. 146,147 Disease-Specific Issues Fontan Fontan circulation is associated with poorer outcomes after transplantation than other CHD diagnoses, with an 8.6-fold increase in relative risk of death. 102 Fontan patients presenting for transplantation with preserved ventricular function but failing Fontan physiology (eg, symptoms and signs of poor cardiac output, raised right atrial pressure, PLE, ascites, and edema) are at higher risk of dying than those who present with HF and reduced ventricular function.…”
Section: Systemic Venous Anomalies In Patients With Situs Inversus Ormentioning
confidence: 99%
“…There were two deaths in the first year in the biventricular group and none in the failed Fontan group [23]. In a series of three pediatric patients undergoing CHLT for failed single ventricle palliation, all three patients were alive at 2, 3 and greater than 5 years respectively [24]. CHLT has also been used to treat a patient with polysplenia and dextrocardia with situs ambiguous [25].…”
Section: Indicationsmentioning
confidence: 99%