Intermediate-Term Outcomes Associated With Kidney Transplantation in Recipients 80 Years and Older: An Analysis of the OPTN/UNOS Database

Abstract

Although perioperative mortality was uncommon among elderly recipients (1.5%), a trend toward higher perioperative mortality was observed in recipients 80 years and older. There was no difference in survival among standard criteria donor and ECD recipients.

Evaluation of Kidney Transplant Candidates: An Update in 2012

“…The authors observed no difference in the rate of acute rejection during the initial hospitalization or at 1 year [19]. In the analysis, 73% of transplant recipients in the 80 years and older group were alive at 2 years [19] exceeding the expectation of the 2-year survival rate of 44% for a dialysis patient aged 80 to 84 years according to the USRDS database [15]. The overall perioperative mortality risk at 30 days was low at 1.5% for the overall cohort of elderly patients with a trend towards a higher perioperative mortality rate at 2.5% for the aged 80 years and older cohort [19].…”

“…The authors observed no difference in the rate of acute rejection during the initial hospitalization or at 1 year [19]. In the analysis, 73% of transplant recipients in the 80 years and older group were alive at 2 years [19] exceeding the expectation of the 2-year survival rate of 44% for a dialysis patient aged 80 to 84 years according to the USRDS database [15].…”

“…In the analysis, 73% of transplant recipients in the 80 years and older group were alive at 2 years [19] exceeding the expectation of the 2-year survival rate of 44% for a dialysis patient aged 80 to 84 years according to the USRDS database [15]. The overall perioperative mortality risk at 30 days was low at 1.5% for the overall cohort of elderly patients with a trend towards a higher perioperative mortality rate at 2.5% for the aged 80 years and older cohort [19]. Among the 80 years and older cohort, death-censored graft failure did not occur more frequently and the mortality rates were similar for SCD or ECD transplant recipients [19].…”

“…Huang et al using data from OPTN/UNOS, compared the outcomes of recipients older than 80 years of age with recipients in the 60 to 69 and 70 to 79 age groups [19]. The 80 years and older cohort had 199 recipients (median age of 81 years) and represented 0.6% of the entire elderly cohort (age greater or equal to 60 years) that was transplanted between 2000 and 2008 in the US.…”

Kidney Transplants for the Elderly

“…Kidney transplantation offers the potential for improved quality and length of life for elderly patients (2-4), and reasonable outcomes have been reported for selected patients in their 70s and even 80s (3,4). However, the proportion of elderly patients on the transplant waiting list and receiving subsequent transplants remains relatively small: Approximately 9% of prevalent ESRD patients 60 or older were on the transplant waiting list in 2008.…”