Intermittent Exposure to Chlorpyrifos Differentially Impacts Neuroreflex Control of Cardiorespiratory Function in Rats

Batista, Thatiany Jardim; Minassa, Vítor Sampaio; Aitken, Andrew Vieira; Jara, Bianca Teixeira; Felippe, Igor; Beijamini, Vanessa; Paton, Julian F. R.; Santos, Leonardo dos; Sampaio, Karla Nívea

doi:10.1007/s12012-019-09528-7

Cited by 13 publications

(2 citation statements)

References 93 publications

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“…However, doses of 10 mg/kg chlorpyrifos in the same rat strain did not elicit significant changes in heart rate [20]. A one-month duration of intraperitoneal chlorpyrifos injection of 7 mg/kg three times weekly in Wistar rats was sufficient to impair brainstem AChE levels significantly more than control values, although heart rate was unaltered [24]. Similarly, it was reported that post-natal day 1 rat pups heart rate was assessed as an indicator for chlorpyrifos-induced neurological effects [25].…”

Section: Discussionmentioning

confidence: 85%

Examination of Urinary Chlorpyrifos Biomarker Concentrations and Heart Rate in a Sample of US Children and Adolescents

LeBeau¹,

Sutherland²,

Bourgeois³

et al. 2020

ODEM

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Section: Discussionmentioning

confidence: 85%

Examination of Urinary Chlorpyrifos Biomarker Concentrations and Heart Rate in a Sample of US Children and Adolescents

LeBeau¹,

Sutherland²,

Bourgeois³

et al. 2020

ODEM

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“…Besides such effects, other biomarkers extensively assessed on rats were cardiovascular and cardiorespiratory dysfunctions (Cunha et al 2018; Batista et al 2019). One of the physiological parameters altered due to AChE decrease is the respiratory rate.…”

Section: Resultsmentioning

confidence: 99%

The Toxic Effects of Glyphosate, Chlorpyrifos, Abamectin, and 2,4‐D on Animal Models: A Systematic Review of Brazilian Studies

Disner

Falcão

Andrade‐Barros

et al. 2020

Integr Envir Assess & Manag

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Brazil is a global agricultural commodity producer and the largest consumer of pesticides. Pesticide use in Brazil comprised 549 280 tons in 2018. In the country, soybean, corn, and sugar cane are extensively produced, which are the most pesticides demanding crops. In the last years, the records of new pesticides were the highest in the historical series. They can persist in soil or water, accumulate in organisms, and contaminate workers and the general population through the air, water, or food. This review aimed to gather toxicological data obtained by animal models exposed to 4 pesticides: glyphosate, chlorpyrifos, abamectin, and 2,4‐D. An additional goal was to compose an overview of how this subject has been approached, surveying which research groups are working on this field, where they are located, and relations with pesticides used in those regions. We collected the papers from the platforms PubMed, Scopus, Scielo, and Web of Science, performed in Brazil from 2014 to 2019. After two‐step blind selection using the software Rayyan QCRI by different authors, 67 studies were selected to extract data. We observed that research is more concentrated in the South region, followed by the Southeast and Midwest, with 43%, 32%, and 23% of the studies, respectively. The prevalent institutions are from the states of Rio Grande do Sul, São Paulo, and Goiás. The effects on a variety of biomarkers help predict the potential risks to humans and nontarget organisms. The prevalent animal model was fish (36%). Overall, the main toxic effects evaluated were mortality, abnormalities in the blood cells, developmental abnormalities, and behavior alterations. Integr Environ Assess Manag 2021;17:507–520. © 2020 SETAC

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Emerging contaminants and their possible bioremediation through bacterial laccases

Romero-Martínez,

Parra-Saldivar,

Trujillo-Roldán

et al. 2024

Bacterial Laccases

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Intermittent Exposure to Chlorpyrifos Differentially Impacts Neuroreflex Control of Cardiorespiratory Function in Rats

Cited by 13 publications

References 93 publications

Examination of Urinary Chlorpyrifos Biomarker Concentrations and Heart Rate in a Sample of US Children and Adolescents

Examination of Urinary Chlorpyrifos Biomarker Concentrations and Heart Rate in a Sample of US Children and Adolescents

The Toxic Effects of Glyphosate, Chlorpyrifos, Abamectin, and 2,4‐D on Animal Models: A Systematic Review of Brazilian Studies

Emerging contaminants and their possible bioremediation through bacterial laccases

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