Intermittent fasting and its impact on toxicities, symptoms and quality of life in patients on active cancer treatment

Li Sucholeiki, Robert; Propst, Casey L.; Hong, David S.; George, Goldy C.

doi:10.1016/j.ctrv.2024.102725

Cancer Treatment Reviews

2024

DOI: 10.1016/j.ctrv.2024.102725

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Intermittent fasting and its impact on toxicities, symptoms and quality of life in patients on active cancer treatment

Robert Li Sucholeiki,

Casey L. Propst,

David S. Hong

et al.

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2024

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Fasting and Diet: Overview in Chronic Lymphocytic Leukemia

Trojani,

Bossi,

Cairoli

2024

Hemato

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Background: This review aims to provide an overview of the potential impact of fasting and diet on cancer, and in particular, on chronic lymphocytic leukemia (CLL), which is the most frequent form of leukemia in the Western world. Methods: Experimental and clinical studies have provided evidence of the crucial role of fasting in enhancing cancer treatment and improving outcomes for oncological patients, particularly at the early stages of the disease. Results: Emerging evidence highlights that fasting creates a differential stress response under critical conditions by fostering the survival of normal cells while limiting the survival and growth of cancer cells. Pivotal studies on CLL have highlighted the potential of fasting and dietary components to influence the stromal microenvironment and certain metabolic pathways, thereby affecting cancer cell apoptosis and immune response. In addition, explorative and initial clinical studies suggest that fasting and specific diets can mitigate the toxicity of chemotherapy. Conclusions: Clinical trials are needed to evaluate the efficacy and safety of nutritional and fasting approaches in cancer and CLL. Future investigations could provide new insights into the potential role of diet and fasting in the prevention and treatment of cancer, potentially leading to more effective and personalized therapeutic strategies.

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Fasting and Diet: Overview in Chronic Lymphocytic Leukemia

Trojani,

Bossi,

Cairoli

2024

Hemato

View full text Add to dashboard Cite

show abstract

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Intermittent fasting and its impact on toxicities, symptoms and quality of life in patients on active cancer treatment

Cited by 1 publication

References 59 publications

Fasting and Diet: Overview in Chronic Lymphocytic Leukemia

Fasting and Diet: Overview in Chronic Lymphocytic Leukemia

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