Intermittent fasting for adults with overweight or obesity

Garegnani, Luis; Oltra, Gisela; Saldías, Cristina; Escobar Liquitay, Camila Micaela; Madrid, Eva

doi:10.1002/14651858.cd015610

Cited by 3 publications

(1 citation statement)

References 53 publications

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“…This comprehension allows for the development of targeted and effective strategies to prevent and manage obesity-related complications. It also provides insights into how lifestyle modifications, such as dietary interventions, can positively influence insulin sensitivity, fat and glucose metabolic health and overall well-being ( 13 ).…”

Section: Introductionmentioning

confidence: 99%

The effect of intermittent fasting on microbiota as a therapeutic approach in obesity

Cadena-Ullauri,

Guevara-Ramírez,

Ruiz-Pozo

et al. 2024

Front. Nutr.

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Obesity, a public health challenge, arises from a complex interplay of factors such as dietary habits and genetic predisposition. Alterations in gut microbiota, characterized by an imbalance between Firmicutes and Bacteroidetes, further exacerbate metabolic dysregulation, promoting inflammation and metabolic disturbances. Intermittent fasting (IF) emerges as a promising dietary strategy showing efficacy in weight management and favoring fat utilization. Studies have used mice as animal models to demonstrate the impact of IF on gut microbiota composition, highlighting enhanced metabolism and reduced inflammation. In humans, preliminary evidence suggests that IF promotes a healthy microbiota profile, with increased richness and abundance of beneficial bacterial strains like Lactobacillus and Akkermansia. However, further clinical trials are necessary to validate these findings and elucidate the long-term effects of IF on microbiota and obesity. Future research should focus on specific tissues and cells, the use of advanced -omics techniques, and exploring the interaction of IF with other dietary patterns, to analyze microbiota composition, gene expression, and potential synergistic effects for enhanced metabolic health. While preliminary evidence supports the potential benefits of IF in obesity management and microbiota regulation, further research with diverse populations and robust methodologies is necessary to understand its implications and optimize personalized dietary interventions. This review explores the potential impact of IF on gut microbiota and its intricate relationship with obesity. Specifically, we will focus on elucidating the underlying mechanisms through which IF affects microbiota composition, as well as its subsequent effects on obesity.

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Section: Introductionmentioning

confidence: 99%

The effect of intermittent fasting on microbiota as a therapeutic approach in obesity

Cadena-Ullauri,

Guevara-Ramírez,

Ruiz-Pozo

et al. 2024

Front. Nutr.

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Scarlett McNally: Preventing obesity is different from curing it—and even more urgent

McNally

2024

BMJ

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Religious and Traditional Fasting May Be an Alternative Method to Tackle Global Health Threats and the Epidemic of Obesity

Armutcu

2024

OBM Integr Complement Med

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Intermittent fasting practices, recommended as a potential nutritional approach against obesity and metabolic diseases, have become increasingly widespread in recent years. Although convincing data on the anti-obesity and cardio-metabolic benefits of intermittent fasting are obtained mostly from experimental studies, religious and traditional fasting practices have been among the treatment methods applied for human health for centuries. Both intermittent fasting and religious fasting may be a promising strategy for weight loss and improving metabolic health as well as combating the obesity pandemic. In this context, in addition to proven experimental and clinical studies, this review suggested that fasting can be one of the important cornerstones of an integrative treatment approach, as it is a religious, traditional, and widely known method worldwide. It also claims that it can be a useful and sustainable method in the fight against both obesity and factors that threaten planetary health.

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Intermittent fasting for adults with overweight or obesity

Cited by 3 publications

References 53 publications

The effect of intermittent fasting on microbiota as a therapeutic approach in obesity

The effect of intermittent fasting on microbiota as a therapeutic approach in obesity

Scarlett McNally: Preventing obesity is different from curing it—and even more urgent

Religious and Traditional Fasting May Be an Alternative Method to Tackle Global Health Threats and the Epidemic of Obesity

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