Intermolecular interactions in the absorption and and fluorescence spectrum of fluorescein sodium

Golubeva, N. G.; Gordienko, V. P.; Velikanov, A. O.

doi:10.1007/bf00661836

Cited by 2 publications

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“…Solvatochromic investigation of fluorescein was already performed, and interesting results were reported in the literature [53][54][55]. Golubeva et al [56] recorded the absorption and fluorescence spectra of fluorescein sodium in water and dimethyl sulfoxide (DMSO) at different values of pH, as well as in healthy and pathological human tissues, drawing some conclusions about the formation of hydrogen bonds. To our knowledge, this is the only study of fluorescein sodium involving solvatochromism.…”

Section: Introductionmentioning

confidence: 99%

On the Solvatochromism of Fluorescein Sodium

Cheptea,

Zara,

Ambrosi

et al. 2024

Symmetry

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Fluorescein sodium is a very important compound for a wide spectrum of applications, from which medical applications prevail. Despite this, there are very few studies in the literature related to the structure and fundamental properties of fluorescein sodium and its solutions, with most of the studies dealing with fluorescein. The purpose of the present article is to determine some parameters of the fluorescein sodium molecule approaching the quantum-mechanical modeling and experimental solvatochromism in both binary and ternary solutions. For data analysis, several theoretical models were applied. The results highlight the intermolecular interactions involved in the spectral shift of the electronic absorption band of fluorescein sodium when dissolved in different solvents or binary solvents and allowed the estimation of the difference between the interaction energy in molecular pairs of the type of fluorescein sodium − solvent 1 and fluorescein sodium − solvent 2. By applying a variational method, the dipole moment in the first excited state of the fluorescein sodium molecule and the angle between the dipole moments in the ground and excited states, respectively, were estimated. These results are useful for a better understanding of the behavior of fluorescein sodium when dissolved in different solvents or combinations of solvents, to develop new practical applications.

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