Internações hospitalares e mortalidade por intoxicação medicamentosa em São Paulo

Oliveira, Janessa de Fátima Morgado de

doi:10.11606/t.6.2017.tde-17042017-083842

Cited by 7 publications

(8 citation statements)

References 14 publications

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“…These differences, based on the specifications of the instructions, do not characterize failure of the technique employed and are in accordance with the study of Rosenblit et al (16) who found a difference of 0.6 g/dL between two automated techniques. Research carried out in Northern England, employing the copper sulphate precipitation technique to screen blood donors also observed differences between tests of 0.24 for men and 2.8 for women (17) . It is recommended that the variations should not exceed 0.3 g/dL when employing the cyanmethemoglobin method (18) .…”

Section: Discussionmentioning

confidence: 99%

Etiology of anemia of blood donor candidates deferred by hematologic screening

Silva¹,

Souza²,

Carlos³

et al. 2012

Revista Brasileira De Hematologia E Hemoterapia

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Objective: Iron deficiency is the most common cause of anemia and one of the main factors in the clinical deferral of blood donors. This fact prompted the current study that aimed to determine the prevalence and etiology of anemia in blood donor candidates and to evaluate the hematological screening technique used for the exclusion of these donors. Methods: This was a prospective study that compared two groups (Anemic and Non-anemic). Initially screening for anemia was performed by manually measuring hemoglobin (Bioclin® Kit); the results were subsequently compared with an automated screening method (Coulter T-890). The etiology was investigated by hemoglobin electrophoresis in alkaline and acid pH, Hb A2 dosage and measurement of the ferritin concentration by immunoagglutination. Differences and associations of interest were analyzed using the Yates and McNemar's Chi-square tests and the Fisher, Mann-Whitney, Wilcoxon and Kruskal-Wallis tests. Results: The deferral rate due to anemia was 4.2%; iron deficiency was identified in 37.5% and beta thalassemia in 9.3% of the excluded candidates. There was a significant discrepancy between the two techniques used to measure hemoglobin with 38.1% of initially deferred donors presenting normal hemoglobin levels by the automated method. Conclusion: The results show a high rate of blood donors being deferred for anemia and confirm that iron deficiency is the most prevalent cause. The discrepancies found by comparing screening methods suggest that hemoglobin and hematocrit levels should be confirmed before deferring a donor due to anemia; this may increase supplies in blood banks.

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Section: Discussionmentioning

confidence: 99%

Etiology of anemia of blood donor candidates deferred by hematologic screening

Silva¹,

Souza²,

Carlos³

et al. 2012

Revista Brasileira De Hematologia E Hemoterapia

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“…The laboratory investigation was performed using selective and diagnostic tests such as the filter paper solubility test (20) , osmotic resistance test in 0.36% saline (21) , erythrocyte morphology (22) and alkaline electrophoresis in cellulose acetate at pH 8.6 (23) . Positive results were confirmed by acid electrophoresis in agarose gel (24) ; hemoglobin (Hb) A 2 (23) was measured when the beta thalassemia trait was suspected and intra-erythrocyte Hb H testing was performed when electrophoresis was positive (25) .…”

Section: Methodsmentioning

confidence: 99%

A model of genetic guidance for hemoglobinopathy patients and laboratory diagnosis of family members as educational and preventive measures

Ferreira¹,

Freire²,

Silveira-Lacerda³

et al. 2012

Revista Brasileira De Hematologia E Hemoterapia

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Background: The high frequency of hemoglobinopathies in Brazil constitutes a public health problem and thus educational and preventive measures are necessary to reduce the incidence. Genetic guidance, a modality of genetic counseling, and family screening are measures that can assist in reproductive decisions and mitigate clinical, psychological and social problems of families with these disorders.Objetive: The objective of the current study was to evaluate the effectiveness of educational and preventive measures for hemoglobinopathies using genetic guidance and laboratory screening of families.Methods: The diagnoses of patients with hemoglobinopathies were confirmed and then the level of knowledge about their disease was evaluated and genetic guidance was provided. Three months later, the level of assimilated information of these patients was evaluated. In addition, laboratory diagnosis of family members was carried out. Results: Diagnosis of sickle cell anemia was confirmed for most patients. Moreover, the majority of the patients who had a low level of knowledge before genetic guidance (68.8%) demonstrated a higher level of assimilated information after the process (81.8%). Almost 70% of the family members had hemoglobin changes and some had hemoglobinopathies(2.6%). They were duly informed about the results of the examinations, which made it possible to investigate further. Conclusion: Genetic guidance and family screening were effective preventive and educational measures that improved the quality of life of patients, preventing complications and sequels and allowed the referral of those who may transmit altered genes for clinical diagnosis and to genetic counseling services.

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“…Diante disto, muitos deles tornam-se contestadores, impulsivos e agressivos, mas ao mesmo tempo imaturos e inseguros . Essa mistura de sentimentos causam angústia, tristeza e medo, que se não forem adequadamente manejados, podem levar à dependência química Sendo o suicídio um problema de saúde pública previnível torna-se imperativo a criação de campanhas de informação sobre esse assunto, que ainda é considerado um tabu na sociedade atual (OLIVEIRA, 2017). Além disso, é importante que as autoridades em saúde promovam a sensibilização e capacitação de profissionais de saúde de todos os níveis de atenção com vistas à detecção precoce de pacientes com ideação suicida (CARVALHO et al, 2017).…”

Section: As Variáveis Sociodemográficas Associadas Especificamente àS...unclassified

Análise epidemiológica das intoxicações por medicamentos em Maringá entre os anos de 2017 e 2021

Rodrigues¹

2022

BJDV

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Introdução: Intoxicação por medicamentos representam um importante problema de saúde pública e está associado a altas taxas de morbimortalidade no Brasil e no mundo. Objetivo: Caracterizar o perfil epidemiológico dos casos de intoxicação medicamentosa notificados em Maringá no período entre 2017 e 2021. Metodologia: Trata-se de um estudo epidemiológico quantitativo e descritivo realizado a partir de dados disponibilizados pelo Sistema Nacional de Agravos e Notificação (SINAN) relativos aos casos de intoxicação exógena por medicamentos notificados no município de Maringá. Resultados: No período analisado foram notificados 3.190 casos de intoxicação por medicamentos. O número de intoxicações foi maior em indivíduos do sexo feminino (71,4%), de raça branca (66%) e com ensino fundamental ou médio completos (65,1%). Os grupos etários mais vulneráveis foram as crianças de 1 e 4 anos (10,3%), os adolescentes de 15 aos 19 anos (17,1%) e adultos de 20 e 39 anos (43,8%). Quanto à circunstância da intoxicação, observou-se que as tentativas de suicídio corresponderam a 73,7% de todos os casos, seguida por uso acidental (14%). A grande maioria, 97% dos 3.190 casos notificados evoluíram para a cura sem sequelas e foram notificados 14 óbitos durante o período estudado (0,2%). Conclusão: A epidemiologia das intoxicações medicamentosas no município de Maringá é consonante com a de outros estudos nacionais de metodologias similares. Considerando a alta prevalência dos eventos toxicológicos com medicamentos no município estudado, destaca-se a importância de ações preventivas e educativas para a população, sobretudo aquelas com maior risco epidemiológico a fim de minimizar os agravos desta natureza.

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Internações hospitalares e mortalidade por intoxicação medicamentosa em São Paulo

Cited by 7 publications

References 14 publications

Etiology of anemia of blood donor candidates deferred by hematologic screening

Etiology of anemia of blood donor candidates deferred by hematologic screening

A model of genetic guidance for hemoglobinopathy patients and laboratory diagnosis of family members as educational and preventive measures

Análise epidemiológica das intoxicações por medicamentos em Maringá entre os anos de 2017 e 2021

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