Internal exposure potential of water-soluble organic molecules in urban PM2.5 evaluated by non-covalent adductome of human serum albumin

Zeng, Yaling; Zhang, Antai; Yang, Xin; Xing, Chunbo; Zhai, Jinghao; Wang, Yixiang; Cai, Baohua; Shi, Shao; Zhang, Yujie; Shen, Zhenxing; Fu, Tzung-May; Zhu, Lei; Shen, Huizhong; Ye, Jianhuai; Wang, Chen

doi:10.1016/j.envint.2024.108492

Cited by 6 publications

(1 citation statement)

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“…Low albumin levels indicate a higher risk of malnutrition, compromising immune function and increasing incision infection risk [87, 88, 89]. Albumin, a signi cant component of human plasma proteins, is crucial in maintaining internal homeostasis [90]. Low albumin levels reduce a patient's immunity, leading to drug absorption and metabolic disorders and complicating wound healing [91,92].…”

Section: Discussionmentioning

confidence: 99%

New Insights into Risk Factors for Postoperative Infections in Colorectal Cancer

Li,

Zhao,

Liu

2024

Preprint

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Background Postoperative incision infections are a significant concern in colorectal cancer surgery, impacting patient recovery and well-being. Identification of key risk factors for infection following colorectal cancer surgery is crucial for improving patient outcomes. Methods A meta-analytical approach was employed to analyze studies published from January 2015 to December 2022, focusing on variables such as body mass index, diabetes, albumin levels, malnutrition, and surgical duration to assess their association with postoperative infection incidence in colorectal cancer patients. Results Analysis of eleven high-quality studies revealed that elevated body mass index, diabetes, low albumin levels, malnutrition, and longer surgical durations were linked to an increased risk of postoperative incision infections. Conversely, laparoscopic procedures demonstrated potential for reducing infection risks. Conclusions Effective preoperative risk assessment and management are vital in preventing postoperative incision infections in colorectal cancer patients. These findings offer actionable insights for clinicians to optimize patient prognoses and enhance overall quality of life outcomes.

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Section: Discussionmentioning

confidence: 99%