Internal standard method for the measurement of doxorubicin and daunorubicin by capillary electrophoresis with in-column double optical-fiber LED-induced fluorescence detection

Fluorometer for Screening of Doxorubicin in Perfusate Solution and Tissue with Solid-Phase Microextraction Chemical Biopsy Sampling

“…The DOX concentration inside the target tissue should be monitored throughout the local chemotherapy procedure to prevent excessive or insufficient dose levels. Various analytical methods have been used to address this problem, including liquid chromatography coupled to mass spectrometry (LC–MS), − capillary electrophoresis, , fluorescence, and Raman , spectroscopy. Typically, solid tumor analysis includes sample preparation steps such as collecting the biopsied tissues and a solid–liquid DOX extraction.…”

Sophisticated and precise: design and implementation of a real-time optical detection system for ultra-fast PCR

“…Therefore, the uorescence acquisition system is partially integrated into the temperature control system in this study, and a special optical reective surface is innovatively designed on the heating sheet to enhance the overall performance of optical detection without affecting [20][21][22] the rapid temperature change. In the optical adaptation module, we discarded the commonly used side light harvesting method and chose to insert an optical ber by punching a small hole of 4 = 1.2 mm at the bottom of the thermal conductivity sheet where the 55°t emperature zone is located.…”

Application of green-synthesized carbon dots for imaging of cancerous cell lines and detection of anthraquinone drugs using silica-coated CdTe quantum dots-based ratiometric fluorescence sensor

“…Anthracycline anticancer antibiotics, such as doxorubicin (DOX) and daunorubicin (DAN), are widely applied to treat cancers such as breast, lungs, ovarian, bladder, acute lymphocytic leukemia, prostate, and neoplastic disease [22][23][24]. Nonetheless, utilizing these drugs at the concentrations above-allowed level in blood may lead to tissue necrosis, marrow suppression, cardiac toxicity, and oral ulcers [23,25]. So, due to the toxicity effects of these drugs, the development of sensitive and simple analytical techniques is of great importance to clinical research.…”