International Consensus Statement on Screening, Diagnosis and Treatment of Substance Use Disorder Patients with Comorbid Attention Deficit/Hyperactivity Disorder

Crunelle, Cleo L.; Brink, Wim van den; Moggi, Franz; Konstenius, Maija; Franck, Johan; Levin, Frances R.; Glind, Geurt van de; Demetrovics, Zsolt; Coetzee, Corné; Luderer, Mathias; Schellekens, Arnt; Matthys, Frieda

doi:10.1159/000487767

Cited by 124 publications

(151 citation statements)

References 50 publications

Supporting

Mentioning

135

Contrasting

Unclassified

Order By: Relevance

“…The third limitation is the reliance on self-report measures for clinical diagnoses. While the ASRS is currently the most widely used and investigated screening tool in individuals with ADHD and comorbid SUD [57], it is also susceptible to reporter's and social desirability biases that may be affected by substance abuse [20][21][22]. Further, certain environmental distractors included in the MOXO-CPT (e.g., images and sounds of pouring wine and a burning cigarette) may impose various levels of emotional load in different study groups.…”

Section: Discussionmentioning

confidence: 99%

Differential Diagnosis in Patients with Substance Use Disorder and/or Attention-Deficit/Hyperactivity Disorder Using Continuous Performance Test

Slobodin

Blankers²,

Kapitány-Fövény

et al. 2020

Eur Addict Res

Self Cite

View full text Add to dashboard Cite

Background: Although substance use disorders (SUD) and attention-deficit/hyperactivity disorder (ADHD) show significant symptomatic overlap, ADHD is often overlooked in SUD patients. Objective: The aim of the present study was to characterize aspects of attention and inhibition (as assessed by a continuous performance test [CPT]) in SUD patients with and without a comorbid diagnosis of ADHD and in healthy controls, expecting the most severe deficits in patients with a combined diagnosis. Methods: The MOXO-CPT version, which incorporates visual and auditory environ-Slobodin et al.broad set of cognitive domains such as planning, working memory, decision-making, inhibition control, and attention. The lack of consistent differences in cognitive performance between the 3 diagnostic groups might be attributed to various methodological aspects (e.g., heterogeneity in severity, type, and duration of substances use). Our results support the view that motor activity should be considered a significant marker of ADHD.

show abstract

Section: Discussionmentioning

confidence: 99%

Differential Diagnosis in Patients with Substance Use Disorder and/or Attention-Deficit/Hyperactivity Disorder Using Continuous Performance Test

Slobodin

Blankers²,

Kapitány-Fövény

et al. 2020

Eur Addict Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…It is therefore crucial that ADHD is identified as soon as possible during SUD treatment. As recommended by an international consensus group, an instrument to identify ADHD should be incorporated into the standard assessment protocol at treatment onset for SUD (Crunelle et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

Interaction between behavioral inhibition and neural alcohol cue-reactivity in ADHD and alcohol use disorder

et al. 2020

View full text Add to dashboard Cite

Rationale Compared to the general population, adult Attention-Deficit / Hyperactivity Disorder (ADHD) is more prevalent in patients with Alcohol Use Disorder (AUD). Impaired behavioral inhibition is a common characteristic in both ADHD and AUD. Relapse risk is increased in patients with AUD and comorbid, untreated ADHD and in AUD patients with increased neural cuereactivity. Objectives In this study, we examined the interaction between neural correlates of behavioral inhibition and alcohol cuereactivity with a hybrid imaging task. Methods Out of 69 adult study participants, we included n = 49 in our final analyses: Individuals had a diagnosis of either AUD (n = 13), ADHD (n = 14) or both (n = 5), or were healthy controls (HC; n = 17). The functional magnetic resonance imaging paradigm aimed to examine the combined effects of both an interference-inhibition task ("Simon-task") and an alcohol cuereactivity task. Instead of segregating by diagnostic group, we pursued a dimensional approach in which we compared measures of AUD and ADHD severity, as well as the interaction of both, using multiple regression analyses. Results The four groups did not differ on the behavioral level on either the inhibition task or the alcohol cue-reactivity task. However, brain activation in frontal control and reward-related regions during completion of the combined tasks were related to ADHD and AUD severity (symptom load). During presentation of both alcohol cues and the inhibition task, participants with higher AUD and ADHD symptom load exhibited greater BOLD (blood oxygen level dependent) responses in subcortical reward-related regions. Conclusions Our findings support the hypothesis that ADHD additionally diminishes inhibition ability in individuals with AUD. This may increase relapse risk when confronted with alcohol cues. Further, it is crucial for patients with comorbid AUD and ADHD to take into account not only reduced cognitive control over behavioral inhibition but also simultaneously heightened alcohol cue-reactivity.

show abstract

“…c) Le trouble déficitaire de l'attention / hyperactivité (TDAH) est fortement associé au développement de troubles liés à l'usage de substances, souvent à un âge très précoce et avec une aggravation plus rapide du trouble de l'usage. Dans une méta-analyse de 29 études, 23,1 % des patients avec un trouble de l'usage avaient également un TDAH de l'adulte [52,53]. La cooccurrence entre conduites addictives et schizophrénies est connue.…”

Section: Addiction Et Troubles Psychiatriquesunclassified

Conduites addictives : faits cliniques

Lucet

Olié

2020

Bulletin de l'Académie Nationale de Médecine

View full text Add to dashboard Cite

Déclaration de liens d'intérêt : aucun *Étant donné le contexte sanitaire épidémique lié au Covid-19 du mois de mars 2020, la présentation orale de cette communication en séance à l'Académie a été reportée. MC : Médecine de l'addiction KW : Addiction Medicine RésuméMalgré les fréquentes comorbidités psychiatriques, le trouble de l'usage de substance doit être appréhendé comme une pathologie autonome par ses déterminants, sa sémiologie et ses modalités évolutives spontanées ou sous traitement. De multiples produits de synthèse sont désormais accessibles via internet : associé à la créativité des chimistes cela a participé à l'émergence de pratiques inédites allant du chemsex au purple drank.Les conduites addictives résultent d'un ensemble de facteurs individuels (vulnérabilités biologique et psychique) et contextuels (disponibilité et banalisation du toxique dans l'environnement). Les pathologies mentales autres sont des facteurs de vulnérabilité à la pathologie addictive, tout comme les conduites addictives peuvent révéler une pathologie émotionnelle ou psychotique.Le médecin se doit d'entendre l'impuissance du malade face au besoin irrépressible de consommer (craving) et proposer une thérapeutique qui peut être chimique (y compris traitement de substitution) et psychologique. Dans la majorité des cas un accompagnement social s'impose pour corriger les effets désocialisants du trouble de l'usage de substances ou des comportements addictifs. AbstractDespite the frequency of psychiatric comorbidities, substance use disorder must be understood as an autonomous pathology due to its own determinants, semiology and possibilities of evolution, either spontaneous or under treatment.The ease of access to multiple synthetic products via the Internet combined with the creativity of chemists are contributing to the emergence of novel practices ranging from chemsex to purple drank.

show abstract

International Consensus Statement on Screening, Diagnosis and Treatment of Substance Use Disorder Patients with Comorbid Attention Deficit/Hyperactivity Disorder

Cited by 124 publications

References 50 publications

Differential Diagnosis in Patients with Substance Use Disorder and/or Attention-Deficit/Hyperactivity Disorder Using Continuous Performance Test

Differential Diagnosis in Patients with Substance Use Disorder and/or Attention-Deficit/Hyperactivity Disorder Using Continuous Performance Test

Interaction between behavioral inhibition and neural alcohol cue-reactivity in ADHD and alcohol use disorder

Conduites addictives : faits cliniques

Contact Info

Product

Resources

About