International Editor: Temporal bone chondroblastoma

Watanabe, Noritake; Yoshida, Kazuhide; Shigemi, Hideo; Kurono, Yuichi; Mogi, Goro

doi:10.1016/s0194-5998(99)70201-9

Cited by 26 publications

(5 citation statements)

References 12 publications

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“…17,20 However, some authors have reported recurrence rates approaching 20%, even after complete tumor removal. [22][23][24] Therefore, surveillance imaging following surgical resection is prudent for early diagnosis of tumor recurrence. In surgical resection, a conservative approach is recommended with a reduction of postoperative morbidity.…”

Section: Discussionmentioning

confidence: 99%

Chondroblastoma- a rare sinonasal tumor: case report and review of literature

Gavendra

Kulkarni

Shah

et al. 2023

Int J Otorhinolaryngol Head Neck Surg

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Chondroblastoma is a benign primary bone tumor that typically develops in the epiphyses of long bones. Chondroblastoma of the craniofacial skeleton is extremely rare, with most cases occurring in the squamosal portion of the temporal bone. In this report, we describe a case of chondroblastoma of the nasal cavity presenting with a left sided nasal mass which was excised with open approach. We review the literature on craniofacial chondroblastomas with particular emphasis on sinonasal lesions.

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Section: Discussionmentioning

confidence: 99%

Chondroblastoma- a rare sinonasal tumor: case report and review of literature

Gavendra

Kulkarni

Shah

et al. 2023

Int J Otorhinolaryngol Head Neck Surg

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“…For example, lesions of the temporal bone often present with hearing loss (49%), cranial neuropathy (43.3%), facial swelling (22.2%), and/or otalgia (19.8%). 8 12 13 14 15 16 17 18 Since the abducens nerve is particularly prone to compression at the clivus where it enters the Dorello canal, 19 chondroblastoma in this region can result in diplopia with lateral rectus palsy and headache.…”

Section: Discussionmentioning

confidence: 99%

“…The squamous portion of temporal bone is the most common site of craniofacial chondroblastoma, likely due to its cartilaginous origin. 10 17 18 Reid et al identified 81 total reported temporal bone cases since 1950. 12 Only 24 extratemporal craniofacial lesions have been reported previously, including chondroblastoma in the region of the temporomandibular joint ( n = 13), the nasal cavity and paranasal sinuses ( n = 5), skull base ( n = 1), skull vault ( n = 4), and nasion ( n = 1, see Table 1 ).…”

Section: Discussionmentioning

confidence: 99%

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Chondroblastoma of the Clivus: Case Report and Review

et al. 2015

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Background and Importance Chondroblastoma is a benign primary bone tumor that typically develops in the epiphyses of long bones. Chondroblastoma of the craniofacial skeleton is extremely rare, with most cases occurring in the squamosal portion of the temporal bone. In this report, we describe the first case of chondroblastoma of the clivus presenting with cranial neuropathy that was treated with endoscopic endonasal resection. We review the literature on craniofacial chondroblastomas with particular emphasis on extratemporal lesions. Case Presentation A 27-year-old woman presented with severe headache, left facial dysesthesias, and diplopia. Physical examination revealed hypesthesia in the left maxillary nerve dermatome, and complete left abducens nerve palsy. Imaging demonstrated an expansile intraosseous mass originating in the upper clivus with extension superiorly into the sella turcica and laterally to involve the medial wall of the left cavernous sinus. The tumor was completely resected via an endoscopic endonasal approach, with postoperative improvement in lateral gaze palsy. Histopathology was consistent with chondroblastoma. Conclusion Chondroblastoma is a rare tumor of the craniofacial skeleton that should be included in the differential diagnosis of an osteolytic lesion of the clivus. Complete surgical resection remains the mainstay of treatment.

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“…The subsequent immunohistochemical examination of the lesion showed reactivity of the neoplastic protein mass for S-100 protein. The presence of S-100 protein in tumor cells differentiates chondroblastoma from giant cell tumor, chondrosarcoma, and aneurismal bone cysts, favoring the diagnosis of chondroblastoma [8, 9, 10]. The temporal lobes revealed extensive proliferation of multinucleated cells.…”

Section: Discussionmentioning

confidence: 99%

Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint

et al. 2011

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We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possible surgical intervention for occlusal abnormalities, trismus, clicking of the TMJ, and hearing impairment. Based on preoperative immunochemical studies showing positive reaction of multinucleated giant cells for S-100 protein, the final diagnosis was chondroblastoma. The surgical approach – postauricular incision and total parotidectomy, with complete removal of the temporal bone, including the TMJ via the extended middle fossa – was successful in preserving facial nerves and diminishing clinical manifestations. This study highlights a misdiagnosed case in an effort to underline the importance of medical examinations and accurate differential diagnosis in cases involving any tumor mass in the temporal bone.

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International Editor: Temporal bone chondroblastoma

Cited by 26 publications

References 12 publications

Chondroblastoma- a rare sinonasal tumor: case report and review of literature

Chondroblastoma- a rare sinonasal tumor: case report and review of literature

Chondroblastoma of the Clivus: Case Report and Review

Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint

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