Comprehensive nursing is a form of nursing services including biological, psychological, social, spiritual and cultural services necessarily performed by nurses. The literature review used an integrative review approach to explain nursing competency. The methods of this study used the theme analysis method by obtaining the data from Science Direct, Pro Quest, Pub Med, Science and Technology Index (SINTA) published from 2010 to 2021 and obtained 16 articles related to the development of instruments, competencies, comprehensive of nursing, nursing students. There were 3 themes of nursing competency. The first is competence related to the biological, psychological, social, spiritual and cultural competence. The second is competence related to caring and etikal knowlede for patients in any conditions and the third is knowledge and information technology competence. The term of competency refers to a comprehensive set of knowledge, skills, attitudes, and ethics required by the nurses to provide a safe and effective services to the clients. A nurse who has nursing competency is most likely capable of implementing the 3 themes of nursing competency.