This paper charts a forward-looking roadmap for open universities, drawing upon their historical evolution and current practices. It advocates a shift toward a universally accessible, personalized education system. At the heart of this proposed advancement lies the customization of learning paths and experiences, where individualized advising and mentorship, and a variety of learning content, resources, and environments are essential. The study underscores the importance of integrating advanced technologies such as artificial intelligence and blockchain into the open and distance education system. Within the discourse, the paper delineates three primary areas for open universities to address: system transformation, expansion of openness, and integration of digital innovation. The concluding part of the paper offers possible strategic recommendations for policymakers and researchers of open universities. The essence of these recommendations is advocating for a universally personalized educational paradigm while making a strong case for addressing the digital divide, fostering strong partnerships at both global and community levels, and supporting the use of the latest technology to its fullest potential. By navigating this transformative journey, open universities are not just participating in the evolution of educational models but also poised to lead a revolution in the broader landscape of higher education.