Background: Internet abuse has had a growing trend among medical students. This practice incurs negative consequences on many aspects of an individual's life, including academic, professional, and communicative status as well as loneliness and sleep quality. These consequences have adverse effects on the quality of patient care and safety, as well as physical and mental health of students. Objectives: The aim of this study was to investigate the relationship between Internet addiction and loneliness, and sleep quality among students of the Nursing and Midwifery Faculty. Methods: This cross-sectional study was conducted on 216 students of Zahedan Nursing and Midwifery Faculty during year 2016. The study population was selected through the stratified random sampling technique. The data were collected using the demographic form, Young'