“…The perception of pain in FM patients after a behavior intervention is a controversial issue and the results reported to date are contradictory. Some studies report a slight decrease in pain with no statistical significance (Comeche & Vallejo, 2012;Redondo et al, 2004), while others report a decrease after participants had followed a cognitive-behavioral therapy (Hassett & Williams, 2011;Ljotsson et al, 2014;Luciano et al, 2014;Nuesch, Hauser, Bernardy, Barth, & Juni, 2013;Sarzi-Puttini et al, 2011); a health education program consisting of four 1-hour sessions conducted in a primary healthcare center significantly improved pain in 65 people with FM (Bosch Romero, Saenz Moya, Valls Esteve, & Vinolas Valer, 2002). The fact that infiltration reduced both depression and pain by the same percentage is consistent with the hypothesis that an improvement in anxiety leads to a significant reduction in pain (P erez-Pareja et al, 2004).…”