The COVID-19 pandemic has led to significant disruptions to global economies, leading to the need for rapid transformation in the manufacturing sector. Industry 6.0, the next stage in the evolution of manufacturing, has emerged as a possible solution to these challenges. It builds on the previous industrial revolutions and incorporates advanced technologies such as artificial intelligence (AI), and the industrial internet of things (IIoT) to create a more efficient and sustainable manufacturing environment. This chapter aims to provide a comprehensive overview of Industry 6.0 and its potential in the post-COVID era. It examines the fundamental principles, objectives, and evolution of industrial revolutions, and outlines the role of Industry 6.0 in promoting sustainable manufacturing practices. Additionally, it explores the potential of Industry 6.0 to provide mass personalization of services and products, enhance production capacity, and improve the fault-free environment as illustrated by a real-world scenario.