Interpenetrating polymer network (IPN) hydrogel microspheres for oral controlled release application

Al3+ ion cross-linked interpenetrating polymeric network microbeads from tailored natural polysaccharides

“…All samples were analyzed in triplicate. The estimation of percentage drug encapsulation efficiency was calculated by following the equation [28].…”

“…Earlier, we have developed the SCMC based IPN system for oral controlled release application [28]. So as a part of our ongoing research work on the application of hydrophilic biopolymers, the present work describes the development and evaluation of IPN hydrogel microspheres composed of SCMLBG and SCMC to encapsulate diclofenac sodium (DS), a model drug with a shorter biological half-life of 1-2 h. The microspheres prepared have been characterized by different techniques to understand their various physicochemical behaviors and in vitro drug release characteristics.…”

Lidocaine permeation from a lidocaine NaCMC/gel microgel formulation in microneedle-pierced skin: vertical (depth averaged) and horizontal permeation profiles

“…Lidocaine microgels formulated on a batch scale was a time NaCMC and gel by high temperature denaturation without boiling the drug [40]. The 'dissolved lidocaine' was filtered using Nylon 6,6 membranes of 0.1 μm pore size (Posidyne membranes, Pall Corporation, Portsmouth, UK) before quantification by HPLC analysis.…”

Influence on variation in process parameters for the design of xanthan-gum-facilitated ethyl cellulose microparticles for intestinal specific delivery

“…The swollen microparticles were weighed. The equilibrium Brought to you by | New York University Bobst Library Technical Services Authenticated Download Date | 5/29/15 2:45 PM water absorbency ( Q ) of the microparticles was calculated by an equation reported previously [13,14] . % Equilibrium water uptake ( Q ) = (mass of swollen sample-mass of dried sample/ mass of dried sample) × 100 (4)…”