Background:Anxiety disorders pose serious public health problems.The data available on anxiety disorders in the transgender population is limited by the small numbers, the lack of a matched controlled population and the selection of a nonhomogenous group of transgender people.Aims:The aims of the study were(1)To determine anxiety symptomatology (based on the HADS) in a non-treated transgender population and to compare them to a general population sample matched by age and gender;(2)To investigate the predictive role of specific variables, including experienced gender, self-esteem, victimization, social support, interpersonal functioning and cross-sex hormone use regarding levels of anxiety symptomatology;(3)To investigate differences in anxiety symptomatology between transgender people on cross-sex hormone treatment and those who are not.Methods:A total of 913 individuals, who self-identified as transgender attending a transgender health service during a three-year period agreed participation. For the first aim of the study 592 transgender people not on treatment were matched by age and gender with 3816 people from the general population. For the second and third aim the whole transgender population was included.
Measurements:Socio-demographic variables and measures of depression and anxiety(HADS), self-esteem(RSE), victimisation(ETS), social support(MSPSS), and interpersonal functioning(IIP-32).Results:Compared with the general population transgender people had a nearly 3-fold increased risk of probable anxiety disorder(all p < .05). Low self-esteem and interpersonal functioning were found to be significant predictors of anxiety symptoms. Trans women on treatment with cross-sex hormones were found to have lower levels of anxiety disorder symptomatology.Conclusions:Transgender people (particularly trans males) have higher levels of anxiety symptoms suggestive of possible anxiety disorders, when compared to the general population. The findings that self-esteem, interpersonal functioning and hormone treatment is associated with lower levels of anxiety symptoms indicate the need for clinical interventions targeting self-esteem and interpersonal difficulties as well as the importance of quick access to transgender health services.