2020
DOI: 10.20944/preprints202001.0228.v1
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Interplay between Mediterranean Diet and Gut Microbiota in the Interface of Autoimmunity: An Overview

Abstract: The nutritional habits regulate the gut microbiota and may provoke and/or prevent autoimmune disease. Western diet is rich in sugars, meat and poly-unsaturated fatty acids, which lead to dysbiosis of intestinal microbiota, disruption of gut epithelial barrier and chronic mucosal inflammation. On the other hand, Mediterranean Diet (MedDiet) is rich in ω3 fatty acids, fruits and vegetables and has anti-inflammatory properties, which can restore gut eubiosis. The effect of MedDiet and its components in … Show more

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Cited by 2 publications
(2 citation statements)
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“…This is very important since the gut microbiota, as a key factor in driving metabolic activities, is involved in the regulation of host immunity. Thus, supporting healthy gut microbiota can help boosting the overall immunity [24,27,82,[113][114][115].…”
Section: Other Diseasesmentioning
confidence: 99%
“…This is very important since the gut microbiota, as a key factor in driving metabolic activities, is involved in the regulation of host immunity. Thus, supporting healthy gut microbiota can help boosting the overall immunity [24,27,82,[113][114][115].…”
Section: Other Diseasesmentioning
confidence: 99%
“…Additionally, The Mediterranean diet which rich in unsaturated fats and fiber may reduce the circulating level of endotoxin from gastrointestinal bacteria that has been proposed as a cause of inflammation [76]. In other words, The Mediterranean dietary patterns possess the ability to restore the gut to normal microbiota homeostasis through its anti-inflammatory effect [90]. Since gut microbial communities are involved in the modulation of the host innate and adaptive immune response so that this approach will play an important role in future therapeutic development for major global infectious diseases [91].…”
Section: Healthy Dietary Patterns 41 Mediterranean Dietmentioning
confidence: 99%