Interproximal grooving of lower second molars in WLH 4

Durband, Arthur C.; Westaway, Michael C.; Rayner, Daniel

doi:10.1080/03122417.2012.11681955

Cited by 2 publications

(2 citation statements)

References 10 publications

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“…The TMRCA for haplogroup S is between 49 and 51 KYA and it may have been one of the first Australian-specific haplogroups to diversify after it evolved from its ancestral N type, which is consistent with the fact that the root of S is only one mutation step from N. The recent mitogenome sequencing of the skeletal remains of WLH4 of Lake Mungo, New South Wales 16 has determined that this individual (chronologically dated to the late Holocene by Durband, et al . 61 ) belonged to haplogroup S2. Our analysis suggests that she belongs to subtype S2a1a, with her closest three maternal living descendants also living in New South Wales, with one individual, W26, residing close to Lake Mungo.…”

Section: Resultsmentioning

confidence: 99%

Aboriginal Australian mitochondrial genome variation – an increased understanding of population antiquity and diversity

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Oven

Wilcox

et al. 2017

Sci Rep

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Aboriginal Australians represent one of the oldest continuous cultures outside Africa, with evidence indicating that their ancestors arrived in the ancient landmass of Sahul (present-day New Guinea and Australia) ~55 thousand years ago. Genetic studies, though limited, have demonstrated both the uniqueness and antiquity of Aboriginal Australian genomes. We have further resolved known Aboriginal Australian mitochondrial haplogroups and discovered novel indigenous lineages by sequencing the mitogenomes of 127 contemporary Aboriginal Australians. In particular, the more common haplogroups observed in our dataset included M42a, M42c, S, P5 and P12, followed by rarer haplogroups M15, M16, N13, O, P3, P6 and P8. We propose some major phylogenetic rearrangements, such as in haplogroup P where we delinked P4a and P4b and redefined them as P4 (New Guinean) and P11 (Australian), respectively. Haplogroup P2b was identified as a novel clade potentially restricted to Torres Strait Islanders. Nearly all Aboriginal Australian mitochondrial haplogroups detected appear to be ancient, with no evidence of later introgression during the Holocene. Our findings greatly increase knowledge about the geographic distribution and phylogenetic structure of mitochondrial lineages that have survived in contemporary descendants of Australia’s first settlers.

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Section: Resultsmentioning

confidence: 99%

Aboriginal Australian mitochondrial genome variation – an increased understanding of population antiquity and diversity

Nagle

Oven

Wilcox

et al. 2017

Sci Rep

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“…Interestingly, they also exhibit a pattern of interproximal tooth wear bilaterally at the second mandibular molars, indicating that some task activity that incorporated repeatedly dragging fibrous material between these teeth had occurred (18). This wear identifies WLH4 as an individual from a traditional hunter-gatherer population and combined with the lack of mineralization in the bone and its position in the stratigraphic sequence at Lake Mungo, indicates that the remains are estimated to be late Holocene in age (∼3,000-500 y B.P.…”

Section: Significancementioning

confidence: 99%

Ancient mtDNA sequences from the First Australians revisited

Heupink

Subramanian

Wright

et al. 2016

Proc. Natl. Acad. Sci. U.S.A.

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The publication in 2001 by Adcock et al. [Adcock GJ, et al. (2001) Proc Natl Acad Sci USA 98(2):537–542] in PNAS reported the recovery of short mtDNA sequences from ancient Australians, including the 42,000-y-old Mungo Man [Willandra Lakes Hominid (WLH3)]. This landmark study in human ancient DNA suggested that an early modern human mitochondrial lineage emerged in Asia and that the theory of modern human origins could no longer be considered solely through the lens of the “Out of Africa” model. To evaluate these claims, we used second generation DNA sequencing and capture methods as well as PCR-based and single-primer extension (SPEX) approaches to reexamine the same four Willandra Lakes and Kow Swamp 8 (KS8) remains studied in the work by Adcock et al. Two of the remains sampled contained no identifiable human DNA (WLH15 and WLH55), whereas the Mungo Man (WLH3) sample contained no Aboriginal Australian DNA. KS8 reveals human mitochondrial sequences that differ from the previously inferred sequence. Instead, we recover a total of five modern European contaminants from Mungo Man (WLH3). We show that the remaining sample (WLH4) contains ∼1.4% human DNA, from which we assembled two complete mitochondrial genomes. One of these was a previously unidentified Aboriginal Australian haplotype belonging to haplogroup S2 that we sequenced to a high coverage. The other was a contaminating modern European mitochondrial haplotype. Although none of the sequences that we recovered matched those reported by Adcock et al., except a contaminant, these findings show the feasibility of obtaining important information from ancient Aboriginal Australian remains.

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Interproximal grooving of lower second molars in WLH 4

Cited by 2 publications

References 10 publications

Aboriginal Australian mitochondrial genome variation – an increased understanding of population antiquity and diversity

Aboriginal Australian mitochondrial genome variation – an increased understanding of population antiquity and diversity

Ancient mtDNA sequences from the First Australians revisited

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