Interreader agreement in different PI-RADS systems in multiparametric prostate magnetic resonance imaging: A head-to-head comparison between PI-RADSv2 and v2.1

Abstract

The purpose of this study is to compare PI-RADSv2 with v2.1 in terms of interreader agreement. Material and Method:Two hundred-two patients who had both multiparametric prostate magnetic resonance imaging (mpMRI) and 12 quadrant systematic biopsies were included in this retrospective study. Acquisition parameters were totally complied with proposal of PI-RADSv2 and 2.1 guidelines. mpMRIs were evaluated by two radiologists independently. Index lesion's score was used to determine diagnostic performance of the systems. Gleason ≥ 3+4 tumors were considered clinically significant prostate cancer (CSCa). Kappa statistic was used to determine interreader agreement on overall PI-RADS scores. Area under the curve (AUC) was calculated in detection of CSCa using receiver operating characteristic curve (ROC).