Interrelationship between calmodulin (CaM) and H2O2 in abscisic acid-induced antioxidant defense in the seedlings of Panax ginseng

Parvin, Shahnaj; Lee, Ok Ran; Gayathri, S.; Khorolragchaa, Altanzul; Kim, Yujin; Devi, Balusamy Sri Renuka; Yang, Deok‐Chun

doi:10.1007/s11033-012-1564-5

Cited by 17 publications

(9 citation statements)

References 49 publications

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“…Endogenous products and environmental factors could result in the production of reactive oxygen species (ROS) and nitrogen metabolites causing cell injury and genetic instability [64], [65]. GSTs are the most important family of phase II isoenzymes known to detoxify a variety of electrophilic compounds, including carcinogens, chemotherapeutic drugs, environmental toxins, and DNA products generated by reactive oxygen species damage to intracellular molecules, chiefly by conjugating them with glutathione [66].…”

Section: Discussionmentioning

confidence: 99%

Association between Glutathione S-Transferase T1 Null Genotype and Gastric Cancer Risk: A Meta-Analysis of 48 Studies

Liu

Han

et al. 2013

PLoS ONE

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BackgroundGlutathione S-transferases (GSTs) have proved to be involved in the detoxifying several carcinogens and may play an important role in carcinogenesis of cancer. Previous studies on the association between Glutathione S-transferase T1 (GSTT1) polymorphism and gastric cancer risk reported inconclusive results. To clarify the possible association, we conducted a meta-analysis of eligible studies.MethodsWe searched in the Pubmed, Embase, and Wangfang Medicine databases for studies assessing the association between GSTT1 null genotype and gastric cancer risk. The pooled odds ratio (OR) and its 95% confidence interval (95%CI) was calculated to assess the strength of the association. A total of 48 studies with a total of 24,440 individuals were ultimately eligible for meta-analysis.ResultsOverall, GSTT1 null genotype was significantly associated with increased risk of gastric cancer (Random-effect OR = 1.23, 95%CI 1.13–1.35, P OR <0.001, I2 = 45.5%). Significant association was also found in Caucasians, East Asians, and Indians (P Caucasians = 0.010; P East Asians = 0.003; P Indians = 0.017). After adjusting for other confounding variables, GSTT1 null genotype was also significantly associated with increased risk of gastric cancer (Random-effect OR = 1.43, 95%CI 1.20–1.71, P OR <0.001, I2 = 48.1%).ConclusionThe meta-analysis provides strong evidence for the significant association between GSTT1 null genotype and increased risk of gastric cancer.

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Section: Discussionmentioning

confidence: 99%

Association between Glutathione S-Transferase T1 Null Genotype and Gastric Cancer Risk: A Meta-Analysis of 48 Studies

Liu

Han

et al. 2013

PLoS ONE

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“…[Ca 2+ ] cyt spiking can activate P. ginseng calmodulin (CaM) (Parvin et al 2012) and calcium-dependent protein kinase (CDPK), a superfamily of protein kinases. The external Ca 2+ similarly changed specific UGRdGT activity and synthesis of ginsenoside Rb1 together with CaM content and CDPK activity in P. notoginseng cells which suggests that CaM and CDPK may regulate biosynthesis of ginsenoside Rb1 in response to external calcium signal by triggering UGRdGT activity (Yue and Zhong 2004).…”

Section: Ca 2+ Signalingmentioning

confidence: 99%

Production of ginseng saponins: elicitation strategy and signal transductions

Rahimi

Kim

Yang

2015

Appl Microbiol Biotechnol

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Ginseng is one of the most important plants in oriental medicine. The pharmacological effects of this medicinal herb are mostly correlated to the major bioactive triterpene saponin, called ginsenoside. Due to the long cultivation period of ginseng and increased ginsenoside level in aged root, we need to develop strategies to increase ginseng productivity in cell and tissue culture in a faster way. Elicitation is already considered to improve the yield of this valuable secondary metabolite; especially, different types, timings, and durations of elicitation could affect the ginsenoside production and heterogeneity. Activation of ginsenoside biosynthetic genes and ginsenoside accumulation mediated by elicitor-induced signaling molecules would be helpful for commercial production of individual ginsenosides. Jasmonic acid is the well-known signaling molecule which mainly involved in ginsenoside accumulation. Ca(2+) spiking and reactive oxygen species, nitric oxide, and ethylene production are other messengers which mediate production of ginsenoside. This review highlights the elicitation strategies for production of the ginsenoside based on the principle of putative signal transduction pathways.

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“…Bogo et al 2012, Deng et al 2012, Kenny et al 2012, Parvin et al 2012, and Zhang et al 2012). In this paper we accept both concepts as useful and valid.…”

Section: Introductionmentioning

confidence: 99%

The Colletotrichum gloeosporioides species complex

Weir¹,

Johnston²,

Damm³

2012

Studies in Mycology

1,301

1,129

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The limit of the Colletotrichum gloeosporioides species complex is defined genetically, based on a strongly supported clade within the Colletotrichum ITS gene tree. All taxa accepted within this clade are morphologically more or less typical of the broadly defined C. gloeosporioides, as it has been applied in the literature for the past 50 years. We accept 22 species plus one subspecies within the C. gloeosporioides complex. These include C. asianum, C. cordylinicola, C. fructicola, C. gloeosporioides, C. horii, C. kahawae subsp. kahawae, C. musae, C. nupharicola, C. psidii, C. siamense, C. theobromicola, C. tropicale, and C. xanthorrhoeae, along with the taxa described here as new, C. aenigma, C. aeschynomenes, C. alatae, C. alienum, C. aotearoa, C. clidemiae, C. kahawae subsp. ciggaro, C. salsolae, and C. ti, plus the nom. nov. C. queenslandicum (for C. gloeosporioides var. minus). All of the taxa are defined genetically on the basis of multi-gene phylogenies. Brief morphological descriptions are provided for species where no modern description is available. Many of the species are unable to be reliably distinguished using ITS, the official barcoding gene for fungi. Particularly problematic are a set of species genetically close to C. musae and another set of species genetically close to C. kahawae, referred to here as the Musae clade and the Kahawae clade, respectively. Each clade contains several species that are phylogenetically well supported in multi-gene analyses, but within the clades branch lengths are short because of the small number of phylogenetically informative characters, and in a few cases individual gene trees are incongruent. Some single genes or combinations of genes, such as glyceraldehyde-3-phosphate dehydrogenase and glutamine synthetase, can be used to reliably distinguish most taxa and will need to be developed as secondary barcodes for species level identification, which is important because many of these fungi are of biosecurity significance. In addition to the accepted species, notes are provided for names where a possible close relationship with C. gloeosporioides sensu lato has been suggested in the recent literature, along with all subspecific taxa and formae speciales within C. gloeosporioides and its putative teleomorph Glomerella cingulata.Taxonomic novelties:Name replacement - C. queenslandicum B. Weir & P.R. Johnst. New species - C. aenigma B. Weir & P.R. Johnst., C. aeschynomenes B. Weir & P.R. Johnst., C. alatae B. Weir & P.R. Johnst., C. alienum B. Weir & P.R. Johnst, C. aotearoa B. Weir & P.R. Johnst., C. clidemiae B. Weir & P.R. Johnst., C. salsolae B. Weir & P.R. Johnst., C. ti B. Weir & P.R. Johnst. New subspecies - C. kahawae subsp. ciggaro B. Weir & P.R. Johnst. Typification: Epitypification - C. queenslandicum B. Weir & P.R. Johnst.

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Interrelationship between calmodulin (CaM) and H2O2 in abscisic acid-induced antioxidant defense in the seedlings of Panax ginseng

Cited by 17 publications

References 49 publications

Association between Glutathione S-Transferase T1 Null Genotype and Gastric Cancer Risk: A Meta-Analysis of 48 Studies

Association between Glutathione S-Transferase T1 Null Genotype and Gastric Cancer Risk: A Meta-Analysis of 48 Studies

Production of ginseng saponins: elicitation strategy and signal transductions

The Colletotrichum gloeosporioides species complex

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