Interruption volontaire de grossesse médicamenteuse à domicile et à l’hôpital : étude d’efficacité et d’acceptabilité

Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review

“…The ORs for complete abortion at home versus in a clinic showed no difference in effectiveness in five studies. 9,24,25,28,29 In three studies (two French, 26,31 one Vietnamese) 30 medical abortion in clinic settings was found to be more effective, while in the study conducted in both Tunisia and Viet Nam abortion at home proved more effective (OR: 2.9; 95% CI:…”

“…Four studies reported the number of women who would recommend medical abortion to a friend (n = 1194). 26,28,29,31 The pooled OR was 2.8 (95% CI: 0.5-17.3). Thus, no difference was found in this respect between women who took misoprostol at home and in clinic.…”

“…200 mg of mifepristone were used, while in the two French studies 600 mg were used. 26,31 The time between mifepristone and misoprostol administration was 48 hours in seven studies, 36-48 hours in one French study 31 and unspecified in another study. 26 All studies used misoprostol 400 µg, given as two tablets of 200 µg where specified.…”

“…In seven studies women were followed up 2 weeks after mifepristone administration, while in one study they were followed up at 10-20 days. 31 Six studies required that participants live or work within 1 hour of the study site. 24,26,27,[29][30][31] In the French studies, women who lived farther than 1 hour away from the referral hospital were ineligible for the home-based protocol but were included in the study.…”

“…Two studies scored 4/4, 24,30 five studies scored 3/4 9,25,27-29 and the two French studies scored 1/4. 26,31 (Appendix B, available at: http://www.mariestopes.org/documents/Home-based%20Medical-Abortion-Systematic-Review-Appendix.pdf ).…”