We construct, for any given ℓ = 1 2 + N 0 , the second-order, linear PDEs which are invariant under the centrally extended Conformal Galilei Algebra.At the given ℓ, two invariant equations in one time and ℓ + 2 ). The spectrum of the ℓ-oscillator, derived from a specific osp(1|2ℓ + 1) h.w.r., is explicitly presented.The two sets of invariant PDEs are determined by imposing (representationdependent) on-shell invariant conditions both for degree 1 operators (those with continuum spectrum) and for degree 0 operators (those with discrete spectrum).The on-shell condition is better understood by enlarging the Conformal Galilei Algebras with the addition of certain second-order differential operators. Two compatible structures (the algebra/superalgebra duality) are defined for the enlarged set of operators. *