The socio-cultural environment influences people's speculation, attitudes, and behavior, including breastfeeding. Socio-cultural factors related to exclusive breastfeeding, one example is found in the Ngalum ethnic community, Papua, where the community does not give colostrum to their babies. Studies using the literature review method that examine socio-cultural factors on exclusive breastfeeding are still limited. Therefore, further studies are needed using the literature review method which aims to analyze various literature to describe the description of exclusive breastfeeding in terms of socio-cultural aspects. The literature in this study was obtained from the Garuda, Proquest, Pubmed, Scopus, and Google Scholar databases and selected using the PRISMA flow diagram. Based on the analysis, it was found that 20 articles mentioned a socio-cultural relationship with exclusive breastfeeding. From the 20 articles, it was found that mothers who exclusively breastfed were mostly respondents with positive sociocultural backgrounds, while mothers who did not exclusively breastfeed were mostly respondents with negative socio-cultures. Positive social culture related to breastfeeding, such as consuming foods that increase milk production, while negative social culture related to breastfeeding, such as giving prelacteal food before the age of 6 months. It is expected that the results of this study will provide useful information to those involved in supporting exclusive breastfeeding in the future.