Intervention during the first 1000 days in Mexico

Abstract

Health systems and society are facing the growing problem of obesity and its accompanying comorbidities. New approaches to reduce these problems must be oriented to population groups in which long-lasting effects of interventions may occur. Biological processes occurring during the first 1000 days of life, which may be modulated by environmental modifications and result in phenotypes with differential risk for noncommunicable chronic disease, constitute an opportunity for interventions. The nutritional and general health conditions of pregnant women and the fetus, as well as toddlers, can be improved with interventions during the first 1000 days, offering pregnancy care, promoting breastfeeding, instructing on the use of complementary foods, and educating on the adequacy of the family dietary patterns for children. Evidence that interventions during this period result in promotion of children’s growth and development, influencing the risk for development of obesity in infancy, is available. In this article, an ongoing program in Mexico City directed to offer continuum of care during the first 1000 days is described.

Longitudinal changes in maternal circulating microRNAs as potential biomarkers of specific events during healthy pregnancy

“…We analyzed samples from a prospective cohort of pregnant women conducted in Mexico City, now known as "CDMX Perinatal Cohort", part of a wider study program aimed at improving conditions during the rst 1,000 days of life [23].…”

Assessing the relationship of maternal short stature with coexisting forms of malnutrition among neonates, infants, and young children of Pakistan

“…This stagnation may be partially attributed to the intergenerational cycle of malnutrition (National Institute of Population Studies (NIPS), P., ICF, 2019;United Nations Children Funds, 2019). The first 1000 days of life offer a critical window of opportunity to break the intergenerational cycle of malnutri tion from parents to offspring (Estrada-Gutiérrez et al, 2020).…”

“…Interventions applied during this period can effectively avert var ious types of nutritional disorders, including CFM, thereby safe guarding children from numerous illnesses through simple and cost-effective interventions (Estrada-Gutiérrez et al, 2020;Jones et al, 2003).…”

A comprehensive intervention package including an egg- and milk-based snack improves the linear growth and dietary diversity of children under two years children in rural Bangladesh: A community-based cluster randomized controlled trial

“…Analyses of early growth patterns across Africa and Asia show stunting begins antenatally, with length-for-age Z-scores (LAZ) declining rapidly in the rst two years 8 . Thus, many interventions emphasize the rst 1,000 days of life, from conception until children's second birthday as a critical window of opportunity 9 . However, the largest proportion of stunting develops during the complementary feeding period (6-23 months) 10 .…”