Interventional Radiologist's perspective on the management of bone metastatic disease

Percutaneous radiofrequency ablation of painful spinal metastasis: a systematic literature assessment of analgesia and safety

“…Accordingly, many patients may potentially benefit from percutaneous treatments after failure of radiation therapy. Although direct comparative studies between percutaneous treatments and radiation therapy are substantially lacking [21], some studies proved that when percutaneous treatments are coupled to radiation therapy for the treatment of painful bone metastasis, high rates of pain relief are achieved compared to radiation therapy alone [22,23]. In the present literature analysis, there were no comparative studies among RFA and RFA plus radiation therapy.…”

Percutaneous Image-Guided Screw Fixation of Bone Lesions in Cancer Patients: Double-Centre Analysis of Outcomes including Local Evolution of the Treated Focus

“…Conversely, surgery is favoured for low-risk patients with isolated solitary bone metastasis and good prognosis, since it offers potentially curative resection and optimal biomechanical reconstruction [10,13,15,34]. Patients between these extremes should ideally be treated with cytoreduction followed by stabilisation-either via limited surgical resection and reconstruction; or using percutaneous thermal ablation with PIGSF/cementoplasty [10,35]. PIGSF with close clinical and radiological monitoring is therefore a viable option for a wide range of patients.…”

Interventional Techniques for the Ablation and Augmentation of Extraspinal Lytic Bone Metastases

“…The current interventional radiology literature describes using ablation, cementoplasty, or a combination of the two when treating patients with extraspinal, non-weight-bearing lesions of long bones which have Mirels' scores of 7 or less. 2,4,30 Weight-bearing lesions, or lesions that have scores of 9 or above, are universally treated with cementoplasty, and are often additionally treated with PS and ablation. 11,14,[32][33][34] The Harrington classifications were developed several years before the Mirels system to guide surgical therapy of metastases and defects within the acetabulum.…”