Interventional radiology techniques for the diagnosis of lymphoma or leukemia

Garrett, Kevin M.; Hoffer, Fredric A.; Behm, Frederick G.; Gow, Kenneth W.; Hudson, Melissa M.; Sandlund, John T.

doi:10.1007/s00247-002-0743-2

Cited by 32 publications

(11 citation statements)

References 9 publications

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“…Of the remaining 196 biopsies, 40 were performed on known oncologic patients suspected of having tumor progression (8) or tumor recurrence (32), and in 156 cases the biopsy was performed to establish diagnosis. Of the remaining 196 biopsies, 40 were performed on known oncologic patients suspected of having tumor progression (8) or tumor recurrence (32), and in 156 cases the biopsy was performed to establish diagnosis.…”

Section: Resultsmentioning

confidence: 99%

“…3,[6][7][8][9]11 Of the 4 cases, we missed on the first biopsy, 3 were secondary to radiologist error in choosing the best sonographic window to sample the suspected site, and soon after a second US-guided biopsy corrected the technical error. 3,[6][7][8][9]11 Of the 4 cases, we missed on the first biopsy, 3 were secondary to radiologist error in choosing the best sonographic window to sample the suspected site, and soon after a second US-guided biopsy corrected the technical error.…”

Section: Discussionmentioning

confidence: 99%

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Ultrasound-guided Core Biopsy as the Primary Tool for Tissue Diagnosis in Pediatric Oncology

Ilivitzki

Abu-Gazala

Arkovitz

et al. 2014

Journal of Pediatric Hematology/Oncology

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Ultrasound-guided Core Biopsy as the Primary Tool for Tissue Diagnosis in Pediatric Oncology

Ilivitzki

Abu-Gazala

Arkovitz

et al. 2014

Journal of Pediatric Hematology/Oncology

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“…Both CT-and US-guided procedures have a reported accuracy of 89%-92% (47)(48)(49). We strongly favor US guidance because it offers real-time needle guidance and does not involve radiation.…”

Section: Diagnostic Role Of Imaging-guided Renal Biopsymentioning

confidence: 93%

“…Core biopsy as well as flow cytometric and immunohistochemical studies are essential in confirming the diagnosis and classifying the tumor prior to therapy, with satisfactory specimens being reported in 69%-82% of cases. The diagnostic yield is higher in cases of non-Hodgkin lymphoma than in cases of Hodgkin disease (47)(48)(49). Immunohistochemical stains are routinely used employing conventional methodology and include leukocyte common antigen, CD20 (B-cell marker), CD3 (T-cell marker), kappa and lambda light chains (to demonstrate clonality in B lymphocytes) and, CD15 and CD30 (Reed-Sternberg cell markers).…”

Section: Diagnostic Role Of Imaging-guided Renal Biopsymentioning

confidence: 99%

Imaging of Renal Lymphoma: Patterns of Disease with Pathologic Correlation

Sheth

Ali²,

Fishman³

2006

RadioGraphics

184

126

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Extranodal spread of lymphoma often affects the genitourinary system, with the kidneys being the most commonly involved organs. Contrast material-enhanced computed tomography (CT) remains the modality of choice for the detection, diagnosis, staging, and monitoring of renal lymphoma. Magnetic resonance (MR) imaging is particularly useful in patients in whom intravenous administration of iodinated contrast material is contraindicated. Ultrasonography (US), although very valuable for diagnosing lymphoma in the testis or epididymis, is less sensitive than CT and MR imaging for detecting renal lymphoma. Typical imaging findings of renal lymphoma include multiple poorly enhancing or hypoechoic masses, retroperitoneal tumors directly invading the kidneys, bilateral renal enlargement, and perirenal soft-tissue masses. Cystic lesions and tumors predominantly affecting the renal sinus and collecting system are uncommon. Unless the renal lesions manifest in the setting of widespread lymphoma, percutaneous biopsy is indicated to differentiate lymphoma from metastases, hypovascular renal cell carcinoma, uroepithelial carcinoma, or atypical infection, with US routinely being used to guide the procedure. Current immunohistochemical techniques allow accurate diagnosis and characterization of renal lymphoma. Radiologists should be familiar with both typical and atypical manifestations of renal lymphoma and should recommend imaging-guided percutaneous biopsy for diagnostic confirmation to avoid unnecessary nephrectomy.

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“…1). Mediastinale Stanzbiopsien bei Verdacht auf Hodgkin-und Non-Hodgkin-Lymphomen zeigten bei Kindern eine Sensitivität von 75 % und eine Spezifität von 100 % [21]. In einer anderen Studie mit überwiegend mediastinalen Punktionen bei 26 Kindern erbrachte die FNAB in 96 % der Fälle adäquates Material für die zytologische Auswertung [22].…”

Section: Thoraxunclassified

Computertomografisch gesteuerte Interventionen bei Kindern

Honnef

Wildberger

Schubert

et al. 2007

Fortschr Röntgenstr

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In pediatric CT-guided interventions specific features have to be taken into account. Due to a lack of cooperation or limited ability to cooperate, procedures are often performed using analgosedation or general anesthesia. To provide radiation protection, justified indication for CT-guided intervention is necessary and sonography and MRI are to be preferred whenever possible. CT examinations also need to be dose-adapted with sequential scanning and a tube voltage and tube current reduction compared to pediatric diagnostic CT studies must be ensured. Gonad shields are recommended for male patients. Biopsy device selection depends on the assumed tumor entity since histology and also immunohistochemical, molecular pathological and cytogenetical analysis are necessary to differentiate pediatric tumors (small, round, blue cell tumors). In addition to diagnostic procedures, therapeutic interventions (drainage, injection therapies, neurolysis, and radiofrequency ablation) can also be used in children and can provide an alternative to surgery in selected cases. With justified indications and precise performance, CT-guided interventions can be successful in pediatric patients with limited risks.

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Interventional radiology techniques for the diagnosis of lymphoma or leukemia

Abstract: Percutaneous biopsy of lymphoma is usually diagnostic. Drainage or aspiration of a fluid collection associated with NHL or leukemia is often diagnostic and is less invasive than biopsy. These procedures are minimally invasive and effective for diagnosing pediatric hematologic malignancies.

Cited by 32 publications

References 9 publications

Ultrasound-guided Core Biopsy as the Primary Tool for Tissue Diagnosis in Pediatric Oncology

Ultrasound-guided Core Biopsy as the Primary Tool for Tissue Diagnosis in Pediatric Oncology

Imaging of Renal Lymphoma: Patterns of Disease with Pathologic Correlation

Computertomografisch gesteuerte Interventionen bei Kindern

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