Interventions for the Management of Computer Vision Syndrome

Singh, Sumeer; McGuinness, Myra B; Anderson, Andrew J.; Downie, Laura E

doi:10.1016/j.ophtha.2022.05.009

Cited by 40 publications

(38 citation statements)

References 85 publications

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“…For treatment of digital eye strain, the growing number of preliminary reports offer promising clinical evidence substantiating the capacity for omega-3 fatty acids to ameliorate signs of ocular surface dysfunction and dry eye-related symptoms. However, it is important to acknowledge a recent systematic review and meta-analysis by Singh et al [ 181 ] that concluded that there is low-certainty evidence of benefits of omega-3 supplementation on reduction of dry eye symptoms in individuals that are symptomatic computer users.…”

Section: Omega-3 Fatty Acidsmentioning

confidence: 99%

“…Consequential decline in this parameter while using computers and handheld devices is believed to correlate with worsening eye fatigue and complaints of visual discomfort [ 211 , 224 ]. Surprisingly, a recent systematic review and meta-analysis, did not report a statistically significant effect on visual fatigue using pooled data from several additional anthocyanin-containing berry extract clinical trials [ 181 ]. Researchers suggest the discrepancy may be attributed, at least in part, to differences in study design regarding visual fatigue questionnaires.…”

Section: Phytochemicalsmentioning

confidence: 99%

“…Among the most prevalent age groups with heavy screen time behaviors before bed, adolescents and young adults represent growing populations that may be particularly vulnerable to psychosocial implications (sleeping disorders, emotional distress, interpersonal anxiety) associated with digital eye strain [ 128 , 129 , 314 , 315 ]. Additionally, while many smartphones market the ability to limit short-wavelength light exposure at night, high-quality clinical evidence to substantiate blue-light attenuating filters along with equivalent ophthalmic lenses to improve sleep quality among healthy individuals is limited and controversial at best [ 26 , 128 , 129 , 181 , 316 , 317 , 318 , 319 ].…”

Section: Carotenoidsmentioning

confidence: 99%

Section: Carotenoidsmentioning

confidence: 99%

“…In a recent systematic review and meta-analysis Singh et al, [ 181 ] evaluated various interventions for management of computer vision syndrome. They found low certainty evidence that suggested the use of omega-3 supplementation in reducing dry eye symptoms, and low certainty evidence of carotenoids improving CFF compared to a placebo [ 181 ]. Singh et al, did not report a statistically significant effect on visual fatigue using pooled data from several additional anthocyanin-containing berry extract clinical trials [ 181 ].…”

Section: Carotenoidsmentioning

confidence: 99%

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Can Nutrition Play a Role in Ameliorating Digital Eye Strain?

Lem

Gierhart²,

Davey

2022

Nutrients

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Digital eye strain is a complex, multifactorial condition that can be caused by excessive screen time exposure to various electronic devices such as smartphones, tablets, e-readers, and computers. Current literature suggests oxidative damage concomitant with a chronic pro-inflammatory state represent significant etiopathogenic mechanisms. The present review aims to discuss the potential dietary role for micronutrients with nutraceutical properties to ameliorate various ocular and vision-related symptoms associated with digital eye strain. For ocular surface dysfunction, enhanced anti-inflammatory benefits with omega-3 polyunsaturated fatty acids have been well documented for treatment of dry eye disease. The anti-oxidative and immunosuppressive properties of anthocyanin phytochemicals may also confer protective effects against visually induced cognitive stress and digital asthenopia. Meanwhile, nutraceutical strategies involving xanthophyll macular carotenoids demonstrate enhanced cognitive functioning and overall visual performance that aids digital eye strain. Collectively, preliminary findings seem to offer a strong line of evidence to substantiate the need for additional randomized controlled trials aimed at treating digital eye strain with adjunctive nutraceutical strategies. Further RCT and comparisons on commercially available nutritional supplements are needed to quantify the clinical benefits.

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Section: Omega-3 Fatty Acidsmentioning

confidence: 99%

Section: Phytochemicalsmentioning

confidence: 99%

Section: Carotenoidsmentioning

confidence: 99%

Section: Carotenoidsmentioning

confidence: 99%

Section: Carotenoidsmentioning

confidence: 99%

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Can Nutrition Play a Role in Ameliorating Digital Eye Strain?

Lem

Gierhart²,

Davey

2022

Nutrients

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Interventions for Dry Eye

McCann,

Kruoch,

Lopez

et al. 2024

JAMA Ophthalmol

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ImportanceDry eye is a common ocular disease that can have substantial morbidity. Systematic reviews provide evidence for dry eye interventions and can be useful for patients, clinicians, and clinical guideline developers. Overviews of reviews use explicit and systematic methods to synthesize findings from multiple systematic reviews, but currently, there are no overviews of systematic reviews investigating interventions for dry eye.ObjectiveTo summarize the results of reliable systematic reviews of dry eye interventions and to highlight the evidence gaps identified.Evidence ReviewWe searched the Cochrane Eyes and Vision US satellite database and included reliable systematic reviews evaluating dry eye interventions published from 2016 to 2022. We reported the proportion of systematic reviews that were reliable with reasons for unreliability. Critical and important outcomes from reliable systematic reviews were extracted and verified. Critical outcomes included dry eye–related patient-reported outcome measures. Results were synthesized from reliable systematic reviews to provide summaries of evidence for each intervention. Evidence for each intervention was defined as conclusive or inconclusive depending on whether high-certainty evidence across systematic reviews was available according to Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) criteria and whether findings reached statistical or clinical significance. Recommendations were made for further research.FindingsWithin the Cochrane Eyes and Vision US satellite database, 138 potentially relevant systematic reviews were identified, 71 were considered eligible, and 26 (37%) were assessed as reliable. Among reliable systematic reviews, no conclusive evidence was identified for any dry eye intervention. Inconclusive evidence suggested that environmental modifications, dietary modifications, artificial tears and lubricants, punctal occlusion, intense pulsed light therapy, vectored thermal pulsation therapy (Lipiflow), topical corticosteroids, topical cyclosporine A, topical secretagogues, and autologous serum may be effective. Only unreliable systematic reviews evaluated lifitegrast, oral antibiotics, and moisture chamber devices.Conclusions and RelevanceThis overview of systematic reviews found some evidence that dry eye interventions may be effective, but no conclusive evidence was available. The conduct and reporting of most systematic reviews for dry eye interventions warrant improvement, and reliable systematic reviews are needed to evaluate lifitegrast, oral antibiotics, and moisture chamber devices.

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