Interventions for treatment of herpes labialis (cold sores on the lips)

Lin, Horng‐Chyuan; Lin, Pei-Tzu; Tsai, Yu-Shiun; Chi, Ching‐Chi

doi:10.1002/14651858.cd015216

Cochrane Database of Systematic Reviews

2022

DOI: 10.1002/14651858.cd015216

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Interventions for treatment of herpes labialis (cold sores on the lips)

Horng‐Chyuan Lin

Pei-Tzu Lin

Yu-Shiun Tsai

et al.

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2024

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Cited by 1 publication

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Atypical Clinical Manifestations of Herpes Simplex Virus-1 Infection

Wicaksono,

Ridho,

Zakiawati

2024

IMCRJ

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Introduction The Herpes Simplex Virus-1 (HSV-1) infection of the oral cavity is a disease that initiates with prodromal symptoms such as fever and malaise, followed by the emergence of oral and perioral lesions. The common clinical manifestations of HSV-1 infection involve the development of vesicles on the face, oral mucosa and lips, which eventually progress to ulceration. This case report aims to present an atypical clinical manifestation of HSV-1 infection. History and Clinical Findings A 62-year-old woman presented with complaints of a lump at the corner of her left lip, which had disappeared but reappeared. Six weeks ago, the lump started as a white spot, then gradually enlarging, becoming painful, and ruptured. The patient went to the clinic for treatment and was given gentamicin ointment, but there was no improvement. Extraoral examination showed a nodule in the corner of the left lip measuring 1 × 2 cm, filled with purulent exudate. Serological examination revealed reactive anti-HSV-1 IgG results, leading to a diagnosis of Herpes Labialis. Case Management Pharmacological therapy comprised antivirals and multivitamins. The lesion resolved after 10 days of treatment with no reported recurrence during the three-month evaluation. Conclusions and Recommendations HSV-1 infection presents with a variety of clinical features, including typical signs of vesicles, ulceration, and also other atypical forms of lesions. A comprehensive history accompanied with supporting examinations is crucial to identifying the diverse clinical manifestations of herpes simplex virus-1 infection.

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Atypical Clinical Manifestations of Herpes Simplex Virus-1 Infection

Wicaksono,

Ridho,

Zakiawati

2024

IMCRJ

View full text Add to dashboard Cite

show abstract

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Interventions for treatment of herpes labialis (cold sores on the lips)

Cited by 1 publication

References 41 publications

Atypical Clinical Manifestations of Herpes Simplex Virus-1 Infection

Atypical Clinical Manifestations of Herpes Simplex Virus-1 Infection

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