Interventions for Vitiligo

Ezzedine, Khaled; Whitton, Maxine E; Pinart, Mariona

doi:10.1001/jama.2016.12399

Cited by 52 publications

(48 citation statements)

References 5 publications

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“…The topical corticosteroid used for vitiligo treatment in the Dr. Soetomo Hospital was clobetasol propionate (a highly potent corticosteroid) 0.05%. This is in accordance with Ezzedine, Whitton, & Pinart (2016), who showed that potent corticosteroids were effective at treating localized and stable lesions.…”

Section: Indications For Nb-uvb Radiation and Topical Corticosteroid supporting

confidence: 92%

Clinical Profiles of Vitiligo With Narrowband Uvb and Topical Corticosteroid Therapy at Dr. Soetomo Hospital

Fauzia

Rahmadewi

Fauziah

2020

JBE

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Background: Vitiligo is a depigmenting disorder that causes a loss of melanocytes in the epidermis. Treatment preferences are based on the characteristics of the vitiligo lesions. Purpose: This study evaluates the clinical profiles of vitiligo treated with narrowband UVB (NB-UVB) radiation and topical corticosteroid therapy in Dr. Soetomo Hospital in 2017. Methods: This study is a retrospective study that uses data from the medical records of vitiligo patients who were treated with NB-UVB radiation and topical corticosteroids in Dr. Soetomo Hospital in 2017. The dependent variable was vitiligo treated with NB-UVB radiation or topical corticosteroids, while the independent variables were disease onset, precipitating factor, duration, stability, amount, affected area, location, and type of vitiligo. Results: Thirty-seven patients (19 females) were included, four of whom had been treated with NB-UVB radiation and 33 with topical corticosteroids. In the NB-UVB radiation group, 75% had stable lesions, 50% had a single lesion, 50% had multiple lesions, 75% had an affected area <10cm 2 , 40% had lesions around their face, 40% had lesions on their extremities, and 75% had focal vitiligo. In the topical corticosteroids group, 75.76% had active lesions, 81.82% had multiple lesions, 81.82% had an affected area <10 cm 2 , 28.21% had lesions around their upper extremities, 28.21% had lesions around their lower extremities, and 45.45% had segmental vitiligo.

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Section: Indications For Nb-uvb Radiation and Topical Corticosteroid supporting

confidence: 92%

Clinical Profiles of Vitiligo With Narrowband Uvb and Topical Corticosteroid Therapy at Dr. Soetomo Hospital

Fauzia

Rahmadewi

Fauziah

2020

JBE

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“…Treatment for at least 2-3 months is needed to determine efficacy of treatment. UV light-based therapy is the most common treatment for vitiligo and, when combined with an additional therapy, is associated with an improved outcome [165].…”

Section: Managementmentioning

confidence: 99%

Vitiligo: A Review

2020

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Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5-2% of the population worldwide. The disease is characterized by the selective loss of melanocytes which results in typical nonscaly, chalky-white macules. In recent years, considerable progress has been made in our understanding of the pathogenesis of vitiligo which is now clearly classified as an autoimmune disease. Vitiligo is often dismissed as a cosmetic problem, although its effects can be psychologically devastating, often with a considerable burden on daily life. In 2011, an international consensus classified segmental vitiligo separately from all other forms of vitiligo, and the term vitiligo was defined to designate all forms of nonsegmental vitiligo. This review summarizes the current knowledge on vitiligo and attempts to give an overview of the future in vitiligo treatment.

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“…18,19 In a meta-analysis study, vitiligo was associated with vitamin D deficiency and topical vitamin D analogues and phototherapy have been shown to be effective in the treatment. 20,21 Alopecia areata is a T-cell mediated disease targeting the hair follicle.…”

Section: Discussionmentioning

confidence: 99%