Interventions pharmaceutiques sur les prescriptions d’antibiotiques en consultations externes de pédiatrie d’un centre hospitalier universitaire de Côte d’Ivoire

Abrogoua, Danho Pascal; Koffi, N’guessan; Doffou, Elisée

doi:10.1016/j.pharma.2015.12.004

Cited by 9 publications

(3 citation statements)

References 30 publications

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“…Infants under 24 months of age were the most affected population with a frequency of 61.9%. Infections, especially of viral origin, are frequent in this age group, which could be explained by the weakness and immaturity of the immune system, and the ease of contamination by those around them [5], [7]. Failure to recognize the preponderance of viral infections in this age group leads to inappropriate prescription of antibiotics.…”

Section: Discussionmentioning

confidence: 99%

“…Concerning the most commonly used antibiotics, amoxicillin was the most prescribed in 37.9% followed by cotrimoxazole in 15.9%. The frequent prescription of amoxicillin is in line with other African studies, it is an easily accessible molecule and considered by many mothers as a treatment for "cough" [7]. According to the recommendations, it remains the first-line treatment for pneumococcal respiratory infections, one of the most common bacterial infections [12], [13].…”

Section: Discussionmentioning

confidence: 99%

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Pre-hospital Consumption of Antibiotics in Children Admitted to the Pediatric Ward of CHU Tambohobe Fianarantsoa

Ramamonjinirina

Rabemananjara

Rakotondravelo³

et al. 2022

EJMED

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Introduction: Antibiotic consumption is on the rise; this increases the risk of bacterial resistance which represents a public health threat with an increasing number of therapeutic impasses. The objective of our study is to evaluate the pre-hospital consumption of antibiotics in children admitted to the pediatric service of CHU-Tambohobe Fianarantsoa. Method: This is a prospective cross-sectional study during a period of 6 months in the pediatric department of the CHU-Tambohobe Fianarantsoa; including all children admitted with antibiotics before their hospitalization. Results: We included 105 cases, i.e. 27.5% of hospitalized patients. The age of our patients ranged from 0 to 180 months with a median age of 24 months. The infectious sites for which antibiotics were prescribed were predominantly respiratory [27.6%] and ENT [24.5%]. Self-medication was used in 11.4% of cases, and 88.6% had consulted a health centre, 76% of whose prescribers were doctors. The antibiotic used was not adapted to the infection site in 54.3% of cases, and the dose was insufficient in 48.27%. The most prescribed antibiotic was Amoxicillin in 37.9% of cases, followed by Cotrimoxazole in 15.9%. The evolution was marked by the absence of improvement which motivated the hospitalization of the child. Conclusion: Our study showed an inappropriate pre-hospital consumption of antibiotics. Continuous training on the correct prescription of antibiotics as well as the implementation of antibiotic therapy protocols are necessary.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pre-hospital Consumption of Antibiotics in Children Admitted to the Pediatric Ward of CHU Tambohobe Fianarantsoa

Ramamonjinirina

Rabemananjara

Rakotondravelo³

et al. 2022

EJMED

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“…For this reason, many lists of IPs have been developed throughout the world. 18,26,27 Some studies carried out in pediatric units in Côte d'Ivoire [28][29][30] showed many DRPs that IP tools in pediatrics (POPI, POPI-UK, PIPc) [22][23][24][25] could not help to detect. For optimal use, a list of IPs must be established by consensus.…”

Section: Introductionmentioning

confidence: 99%

Expert Consensus on a List of Inappropriate Prescribing after Prescription Review in Pediatric Units in Abidjan, Côte d’Ivoire

Doffou¹,

Avi²,

Yao³

et al. 2021

IPRP

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Introduction Inappropriate prescribing (IP) includes inappropriate prescription and omission of prescription. IP can adversely affect the quality of health care in pediatric units. A list of IP taking into account frequently encountered drug-related problems (DRPs) can be useful to optimize prescriptions in pediatrics. The aim of this study was to validate by expert consensus a list of IP after a prescription review in pediatric units in Abidjan. Materials and Methods A list of IPs was developed from a prescription review of inpatients and outpatients aged 1 month to 15 years and followed in pediatric units at teaching hospitals of Abidjan during 16 months. A two-round Delphi method was used to validate a qualitative list of IPs by experts according to their level of agreement on a six-point Likert scale of 0–5 (0, no opinion; 5, strongly agree). Only propositions obtaining the agreement (rating 4 or 5) of >70% of experts who gave a non-zero rating for the first round and 80% for the second round were retained. Results A qualitative list of 54 IPs was drawn up from 267 DRPs detected after prescription review of 4,992 prescription lines for 881 patients. Our panel comprised 22 pediatricians (96%) and one clinical pharmacist (4%). Mean agreement ratings were 4.43/5 (95% CI 4.39–4.48) and 4.6/5 (95% CI 4.56–4.64), respectively, during the first Delphi round and the second ( p <0.001). At the end of the first round, all items submitted (54) were retained, including 13 items that had been reworded. In the second round, 20 experts participated and two IPs (4%) were not retained for the final list. This list comprised 52 IPs (44 inappropriate prescriptions and eight omissions of prescription). Conclusion The list of IP validated in this study should help in the detection of DRPs and optimize prescriptions in pediatric units in Côte d’Ivoire.

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Problèmes liés à la thérapeutique en pédiatrie : incidence, profil et facteurs liés à leur survenue dans les centres hospitaliers et universitaires d’Abidjan (Côte d’Ivoire)

Oriadjé

Boua

Armandine

et al. 2022

Le Pharmacien Clinicien

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Interventions pharmaceutiques sur les prescriptions d’antibiotiques en consultations externes de pédiatrie d’un centre hospitalier universitaire de Côte d’Ivoire

Cited by 9 publications

References 30 publications

Pre-hospital Consumption of Antibiotics in Children Admitted to the Pediatric Ward of CHU Tambohobe Fianarantsoa

Pre-hospital Consumption of Antibiotics in Children Admitted to the Pediatric Ward of CHU Tambohobe Fianarantsoa

Expert Consensus on a List of Inappropriate Prescribing after Prescription Review in Pediatric Units in Abidjan, Côte d’Ivoire

Problèmes liés à la thérapeutique en pédiatrie : incidence, profil et facteurs liés à leur survenue dans les centres hospitaliers et universitaires d’Abidjan (Côte d’Ivoire)

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