Interventions to Reduce Drug Use Among Methamphetamine Users at Risk for HIV

Corsi, Karen F.; Shoptaw, Steven; Alishahi, Musheng; Booth, Robert E.

doi:10.1007/s11904-019-00423-y

Cited by 14 publications

(7 citation statements)

References 66 publications

(84 reference statements)

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“…Future efforts to refine these interventions may involve contingency management, which has been shown to be effective for treating stimulant use. [57][58][59] Finally, as in most simulation studies, the uncertainty quantification in this model is restricted to considering the stochasticity between model runs; the full range of model uncertainty, both due to the complexity of modeling human behavior and unforeseen developments in policy and treatment is likely much greater, and difficult to fully account for. 26,62 * Persons always adherent to ART experiencing imperfect adherence due to stimulant use are uniformly distributed across the three other categories (usually, sometimes, and never adherent).…”

Section: Discussionmentioning

confidence: 99%

Stimulant use interventions may strengthen ‘Getting to Zero’ HIV elimination initiatives in Illinois: Insights from a modeling study

Lee

Sheeler

Hotton

et al. 2022

International Journal of Drug Policy

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Section: Discussionmentioning

confidence: 99%

Stimulant use interventions may strengthen ‘Getting to Zero’ HIV elimination initiatives in Illinois: Insights from a modeling study

Lee

Sheeler

Hotton

et al. 2022

International Journal of Drug Policy

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“…Fourth, future iterations of the model may consider contingency management and related interventions useful for treating stimulant dependency. [56][57][58] This work begins to test empirically interventions in a simulation model designed for a YBMSM population. Future interventions, particularly culturally sensitive interventions for YBMSM who use stimulants are much needed, given their unique contexts of use, and the limited resources and safety nets for substance using YBMSM, relative to White populations.…”

Section: Discussionmentioning

confidence: 99%

Stimulant Use Interventions May Strengthen ‘Getting to Zero’ Initiatives in Illinois: Insights from a Modeling Study

Lee

Sheeler

Hotton

et al. 2021

Preprint

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Objective(s): Young Black men who have sex with men (YBMSM) are a key population identified in the Illinois Getting to Zero (GTZ) initiative who have experienced disproportionate HIV incidence. Rising stimulant use has been determined to impede the effectiveness of ART and pre-exposure prophylaxis for suppressing HIV transmission in populations. This modeling study explores the impact of stimulant use on HIV incidence among YBMSM, given the limited development of dedicated or culturally appropriate interventions for this population, and assesses the impact of these interventions on downstream HIV transmission in the context of achieving GTZ goals. Methods: A previously developed agent-based network model (ABNM), calibrated using data for YBMSM in Illinois, was extended to incorporate the impact of stimulant use (methamphetamines, crack/cocaine, and ecstasy) on sexual networks and engagement in HIV treatment and prevention continua. The model simulated the impact of a residential behavioral intervention (BI) for reducing stimulant dependency and an outpatient biomedical intervention (mirtazapine) for treating methamphetamine dependence on improved engagement in the HIV treatment and prevention continua. The downstream impact of these interventions on population-level HIV incidence was the primary intervention outcome. Results: Baseline simulated annual HIV incidence in the ABNM was 6.9(95% CI: 6.83,7.04) per 100 person years (py) and 453 (95% CI: 445.9,461.2) new infections annually. A residential targeted to 25% of stimulant users yielded a 27.1% decline in the annual number of new infections. Initiating about 50% of methamphetamine users on mirtazapine reduced the overall HIV incidence by about 11%. A 25% increase in antiretroviral treatment (ART) and preexposure prophylaxis (PrEP) uptake in the non-stimulant using YBMSM population combined with a 25% uptake of BI for stimulant users produces an HIV incidence consistent with HIV elimination targets (about 200 infections/year) identified in the GTZ initiative. Conclusions: Targeted behavioral and biomedical interventions to treat stimulant dependency are likely to provide additive benefits to expanding ART and PrEP uptake for everyone in accomplishing GTZ initiatives for HIV elimination.

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“…For example, contingency management is effective at reducing cocaine use among patients in OAT [66] and in iOAT [12]. Both contingency management [67–69] and cognitive behavioural approaches [70,71] have also been shown to reduce methamphetamine use, however, evidence of the effectiveness of psychosocial interventions for methamphetamine use are lacking among OAT patients and thus warrant investigation in this population.…”

Section: Discussionmentioning

confidence: 99%

Self‐managing illicit stimulant use: A qualitative study with patients receiving injectable opioid agonist treatment

Palis

Harrison

Macdonald

et al. 2020

Drug and Alcohol Review

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Introduction and Aims. Illicit stimulant use is prevalent among patients receiving injectable opioid agonist treatment (iOAT) and has been associated with early treatment discontinuation and illicit opioid use. Despite these concerns, little is known about the use of illicit stimulants in this population. As such, this study aimed to explore the processes by which patients receiving iOAT engage in the use of illicit stimulants. Design and Methods. One-on-one in-depth qualitative interviews were conducted. Data collection and analysis followed an iterative approach of coding, searching for meaning, and returning to data collection to saturate categories and explicate relationships between them. Participants were patients receiving iOAT in Vancouver, Canada that reported the use of illicit stimulants (n = 31). Results. The process of 'self-managing illicit stimulant use' was constructed from the data. This process was made up of three interrelated categories reflecting participants' engagement in illicit stimulant use: (i) distancing from the street environment; (ii) taking control of use; and (iii) mobilising support (clinical and social). Discussion and Conclusions. For patients with opioid use disorder and concurrent stimulant use disorder, access to iOAT can promote the self-management of illicit stimulant use. Daily visits to the clinic for opioid agonist treatment present an important opportunity to offer services and supports for patients who use illicit stimulants. Interventions can be guided by patients, recognising them as experts in the management of their stimulant use.

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Interventions to Reduce Drug Use Among Methamphetamine Users at Risk for HIV

Cited by 14 publications

References 66 publications

Stimulant use interventions may strengthen ‘Getting to Zero’ HIV elimination initiatives in Illinois: Insights from a modeling study

Stimulant use interventions may strengthen ‘Getting to Zero’ HIV elimination initiatives in Illinois: Insights from a modeling study

Stimulant Use Interventions May Strengthen ‘Getting to Zero’ Initiatives in Illinois: Insights from a Modeling Study

Self‐managing illicit stimulant use: A qualitative study with patients receiving injectable opioid agonist treatment

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