Interventions Triggered During Routine Use of NIRS Cerebral Oxygenation Monitoring in Cardiac Surgical Patients

Abstract

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Association of Early Perioperative Stroke After Cardiothoracic Surgery with Intraoperative Regional Cerebral Oxygenation Using Near-Infrared Spectroscopy: Comparing Affected Versus Non-Affected Hemispheres

“…There was no signi cant event difference (n = 125) between the intervention and control groups (P = 0.80). A recent observational study on determining the incidence and type of interventions on ScO 2 desaturation below 20% from baseline in 1972 cardiac surgery patients showed no signi cant difference in postoperative stroke (n = 51) between patients with desaturation and those without (P = 0.207) [21].…”

Differential responses of cerebral and renal oxygenation to altered perfusion conditions during experimental cardiopulmonary bypass in sheep

“…NIRS is now routinely used for monitoring cerebral oxygenation and autoregulation of cerebral blood flow 21 in many clinical centres during cardiac surgery, although its efficacy in guiding the deployment of interventions in routine surgery is still a matter of debate. 22 Regardless, the devices used in operating theatres around the world, including the device used in the current study (INVOS5100C), were designed and optimized for use in human patients, not sheep. 23 To assess the validity of NIRS in sheep, we performed an experiment in which sheep undergoing CPB were subjected to variations in the oxygen content of air delivered to the membrane oxygenator.…”