Intestinal and Extra-intestinal Complications of Typhoid Fever: an Update

Gaba, Saurabh; Gupta, Meena; Jesrani, Gautam; Gupta, Samiksha; Gaba, Ruchi; Lehl, Sarabmeet Singh

doi:10.1007/s40475-023-00285-w

Curr Trop Med Rep

2023

DOI: 10.1007/s40475-023-00285-w

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Intestinal and Extra-intestinal Complications of Typhoid Fever: an Update

Saurabh Gaba

Meena Gupta

Gautam Jesrani

et al.

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2024

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Cited by 2 publications

References 48 publications

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Typhoid fever presenting as neuropsychiatric oddities: A case report

Badole,

Singh,

Wasnik

et al. 2024

Asian Pacific Journal of Tropical Medicine

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Rationale: Salmonella is a common etiological agent behind the tropical fever syndrome in the Indian subcontinent. Its prevalence in India remains high due to a lack of proper sanitation services in large parts of the country. Its neuropsychiatric manifestations is rare and the understanding on their pathophysiology is still poor. Patient concerns: A 19-year-old male, presented with a 10-day history of altered mental status, high-grade fever and violent behaviour. 2 Days prior to admission, he developed decreased responsiveness and a muttering delirium with self-talking. Diagnosis: Coma vigil secondary to salmonellosis. Interventions: Intravenous ceftriaxone and dexamethasone. Outcomes: The resolution of the coma vigil and the associated Salmonella infection were observed; however, the patient developed residual mutism. Lessons: The atypical presentation of a globally obtunded state followed by mutism in typhoid coma in this case should be brought to the attention of clinicians worldwide. Additionally, the enduring speech limitations and potential psychiatric consequences may be linked to the prolonged duration of the infection.

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Typhoid fever presenting as neuropsychiatric oddities: A case report

Badole,

Singh,

Wasnik

et al. 2024

Asian Pacific Journal of Tropical Medicine

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Enteric fever in a young man with bowel wall thickening and hepatosplenomegaly

Suarez-Silva,

Katime Zúñiga,

Calderon

et al. 2024

Rev Gastroenterol Peru

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Typhoid fever (enteric fever), caused by Salmonella enterica subsp. enterica serovar Typhi (S. Typhi), is a public health problem especially in South Asia and sub-Saharan African countries, while incidence remains low in most other parts of the world, where the disease is primary related to recent travel to endemic countries or contact with chronic carriers. The diagnosis of typhoid fever is challenging in endemic countries, often also low- and middle- income countries (LMIC), due to the poor sensitivity/specificity of available serologic tests and lack of adequate infrastructure for blood cultures. We report the case of an 18-year-old male patient with a 21-day history of right-sided abdominal pain, malaise, headache, intermittent fever and watery diarrhea. Contrast-enhanced abdominal computed tomography (CT) exhibits thickening of the terminal ileum, cecum and ascending colon with mesenteric lymphadenopathy. Laboratory findings indicate elevated transaminases, positive blood culture to S. Typhi and a positive Widal test to S. Paratyphi A, B and S. Typhi H (flagellar) antigens. A diagnosis of complicated typhoid fever was made. Following a 13-day regimen of ceftriaxone, all symptoms resolved. Few reports have been made about CT manifestations in patients with typhoid fever. While CT can aid in diagnosis, it is particularly important for identifying complications of typhoid fever such as perforation, bleeding and abscess formation.

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Intestinal and Extra-intestinal Complications of Typhoid Fever: an Update

Cited by 2 publications

References 48 publications

Typhoid fever presenting as neuropsychiatric oddities: A case report

Typhoid fever presenting as neuropsychiatric oddities: A case report

Enteric fever in a young man with bowel wall thickening and hepatosplenomegaly

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