Intestinal and gastric tonometry during experimental burn shock

Cancio, Leopoldo C.; Kuwa, Toshiyuki; Matsui, Kenichi; Drew, Guy A.; Galvez, Eleuterio; Sandoval, Laura Lisa; Jordan, Bryan S.

doi:10.1016/j.burns.2006.11.013

Cited by 3 publications

(1 citation statement)

References 40 publications

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“…In order to monitor these perfusion irregularities, several techniques have been used over the years. Human GI perfusion has been monitored by means of tonometry (50)(51)(52), laser Doppler flowmetry (53,54), reflectance spectrophotometry (55), near-infrared spectroscopy (56), orthogonal polarisation spectral imaging, (57,58), indocyanine green clearance (59), and measurements of plasma D-lactate (60). While the outcome of patients with septic shock can be predicted, these techniques cannot be compared to each other since they measure different constituents of GI perfusion (61).…”

Section: Gastrointestinal Perfusion Monitoringmentioning

confidence: 99%

Microdialysis Monitoring of Biomarkers for Early Recognition of Intestinal Ischemia

Priya¹,

Córcoles²

2012

Sepsis - An Ongoing and Significant Challenge

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Section: Gastrointestinal Perfusion Monitoringmentioning

confidence: 99%

Microdialysis Monitoring of Biomarkers for Early Recognition of Intestinal Ischemia

Priya¹,

Córcoles²

2012

Sepsis - An Ongoing and Significant Challenge

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Autophagy can alleviate severe burn-induced damage to the intestinal tract in mice

Zhang

Qiu

Wang

et al. 2017

Surgery

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Evaluation of Multiple Modes of Oximetry Monitoring as an Index of Splanchnic Blood Flow in a Newborn Lamb Model of Hypoxic, Ischemic, and Hemorrhagic Stress

Ramsingh¹,

Dorotta²,

Sanghvi³

et al. 2013

Shock

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Early and aggressive treatment of circulatory failure is associated with increased survival, highlighting the need for monitoring methods capable of early detection. Vasoconstriction and decreased oxygenation of the splanchnic circulation are a sentinel response of the cardiovasculature during circulatory distress. Thus, we measured esophageal oxygenation as an index of decreased tissue oxygen delivery caused by three types of ischemic insult, occlusive decreases in mesenteric blood flow, and hemodynamic adaptations to systemic hypoxia and simulated hemorrhagic stress. Five anesthetized lambs were instrumented for monitoring of mean arterial pressure, mesenteric artery blood flow, central venous hemoglobin oxygen saturation, and esophageal and buccal microvascular hemoglobin oxygen saturation (StO2). The sensitivities of oximetry monitoring to detect cardiovascular insult were assessed by observing responses to graded occlusion of the descending aorta, systemic hypoxia due to decreased FIO2, and acute hemorrhage. Decreases in mesenteric artery flow during aortic occlusions were correlated with decreased esophageal StO2 (R2 = 0.41). During hypoxia, esophageal StO2 decreased significantly within 1 min of initiation, whereas buccal StO2 decreased within 3 min, and central venous saturation did not change significantly. All modes of oximetry monitoring and arterial blood pressure were correlated with mesenteric artery flow during acute hemorrhage. Esophageal StO2 demonstrated a greater decrease from baseline levels as well as a more rapid return to baseline levels during reinfusion of the withdrawn blood. These experiments suggest that monitoring esophageal StO2 may be useful in the detection of decreased mesenteric oxygen delivery as may occur in conditions associated with hypoperfusion or hypoxia.

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Intestinal and gastric tonometry during experimental burn shock

Cited by 3 publications

References 40 publications

Microdialysis Monitoring of Biomarkers for Early Recognition of Intestinal Ischemia

Microdialysis Monitoring of Biomarkers for Early Recognition of Intestinal Ischemia

Autophagy can alleviate severe burn-induced damage to the intestinal tract in mice

Evaluation of Multiple Modes of Oximetry Monitoring as an Index of Splanchnic Blood Flow in a Newborn Lamb Model of Hypoxic, Ischemic, and Hemorrhagic Stress

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