Intestinal lymphoma—a review of the management of emergency presentations to the general surgeon

Abstract

There is a lack of quality evidence for the elective and emergency treatment of NHL involving the small and large intestine. There is a lack of information regarding the impact an emergency presentation has on the timing of postoperative chemotherapy and overall prognosis. It is proposed that in order to develop evidence-based treatment protocols, there should be an intestinal NHL registry.

Primary small intestinal non-Hodgkin lymphomas that have been diagnosed after emergency surgery

“…In stages III-IV, ideal treatment is less clear. [17][18][19] Three of our patients died in the first month due to postoperative complications, 1 patient died after 4 months, and 1 patient died after 5.5 years. Total of 12 patients received CHOP regimen after initial surgery.…”

Successful management of unresectable small bowel lymphoma with laparoscopy‐assisted surgical exclusion of the affected intestine

“…Surgical resection of the involved loop is preferable for resectable SBL. However, the management of unresectable SBL remains unsettled . Here, we demonstrate an effective strategy for unresectable SBL with surgical exclusion of the affected intestine before the systemic chemotherapy.…”

“…The incidence of small bowel lymphoma (SBL) has been increasing worldwide . The greatest concern in its management is the risk of life‐threatening complications, such as perforation, bleeding, and obstruction, which may occur after chemotherapy . These complications worsen a patient's condition and delay the therapeutic schedule, which can result in poor prognosis.…”

Development and internal validation of a risk scoring system for gastrointestinal events requiring surgery in gastrointestinal lymphoma patients

“…Gastrointestinal (GI) lymphoma constitutes 12–22% of all cases of non‐Hodgkin's lymphoma . Management of GI lymphoma carries a risk of severe GI events, such as perforation, obstruction, and bleeding, which may require surgery . These events can occur either at diagnosis or during chemotherapy.…”