Intestinal Microbiota of Dogs and Cats: a Bigger World than We Thought

Suchodolski, Jan S.

doi:10.1016/j.cvsm.2010.12.006

Cited by 107 publications

(93 citation statements)

References 45 publications

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“…Quantitative data not only depend on host characteristics, such as age, gastrointestinal disease and environment, but also on the sample collection method, and the enumeration technique (culture plating v. molecular techniques). An overview of studies investigating the effects of these factors is given in Tables 1 and 2. For a review of different enumeration techniques, their advantages and disadvantages, see Suchodolski (20) .…”

Section: Bacterial Populations In the Gastrointestinal Tractmentioning

confidence: 99%

Dietary fibre and the importance of the gut microbiota in feline nutrition: a review

2014

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Domestic cats are obligate carnivores and in this light hindgut fermentation has been considered unimportant in this species. However, a diverse microbiota has been found in the small and large intestines of domestic cats. Additionally, in vitro and in vivo studies support the hypothesis that microbial fermentation is significant in felines with potential benefits to the host. Results on microbiota composition and microbial counts in different regions of the feline gastrointestinal tract are compiled, including a description of modulating host and technical factors. Additionally, the effects of dietary fibre supplementation on the microbiota composition are described. In a second section, in vitro studies, using inocula from fresh feline faeces and focusing on the fermentation characteristics of diverse plant substrates, are described. In vivo studies have investigated the effects of dietary fibre on a broad range of physiological outcomes. Results of this research, together with studies on effects of plant fibre on colonic morphology and function, protein and carbohydrate metabolism, and the effects of plant fibre on disease conditions that require a decrease in dietary protein intake, are shown in a third section of the present review. Conclusively, for fructans and beet pulp, for example, diverse beneficial effects have been demonstrated in the domestic cat. Both dietary fibre sources are regularly used in the pet food industry. More research is warranted to reveal the potential benefits of other fibre sources that can be used on a large scale in feline diets for healthy and diseased cats.

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Section: Bacterial Populations In the Gastrointestinal Tractmentioning

confidence: 99%

Dietary fibre and the importance of the gut microbiota in feline nutrition: a review

2014

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“…To study the role of the microbiome in this process, we performed culture‐independent analysis of the microbiome. Culture‐independent technique has been used in microbiome studies of dog 19, 20. Culture‐independent technique approach allowed us to bypass the isolation and cultivation of individual species and improved our ability to identify obesity‐associated microbial changes in the gut 21, 22…”

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confidence: 99%

Association of Obesity with Serum Leptin, Adiponectin, and Serotonin and Gut Microflora in Beagle Dogs

Park

Lee

Kim

et al. 2014

Veterinary Internal Medicne

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BackgroundSerotonin (5‐hydroxytryptamine, 5HT) is involved in hypothalamic regulation of energy consumption. Also, the gut microbiome can influence neuronal signaling to the brain through vagal afferent neurons. Therefore, serotonin concentrations in the central nervous system and the composition of the microbiota can be related to obesity.ObjectiveTo examine adipokine, and, serotonin concentrations, and the gut microbiota in lean dogs and dogs with experimentally induced obesity.AnimalsFourteen healthy Beagle dogs were used in this study.MethodsSeven Beagle dogs in the obese group were fed commercial food ad libitum, over a period of 6 months to increase their weight and seven Beagle dogs in lean group were fed a restricted amount of the same diet to maintain optimal body condition over a period of 6 months. Peripheral leptin, adiponectin, 5HT, and cerebrospinal fluid (CSF‐5HT) levels were measured by ELISA. Fecal samples were collected in lean and obese groups 6 months after obesity was induced. Targeted pyrosequencing of the 16S rRNA gene was performed using a Genome Sequencer FLX plus system.ResultsLeptin concentrations were higher in the obese group (1.98 ± 1.00) compared to those of the lean group (1.12 ± 0.07, P = .025). Adiponectin and 5‐hydroytryptamine of cerebrospinal fluid (CSF‐5HT) concentrations were higher in the lean group (27.1 ± 7.28) than in the obese group (14.4 ± 5.40, P = .018). Analysis of the microbiome revealed that the diversity of the microbial community was lower in the obese group. Microbes from the phylum Firmicutes (85%) were predominant group in the gut microbiota of lean dogs. However, bacteria from the phylum Proteobacteria (76%) were the predominant group in the gut microbiota of dogs in the obese group.Conclusions and Clinical ImportanceDecreased 5HT levels in obese group might increase the risk of obesity because of increased appetite. Microflora enriched with gram‐negative might be related with chronic inflammation status in obese dogs.

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“…It is also possible that the aetiology of this syndrome is more complex than a simple infection with one pathogen. Recent advances in molecular techniques have allowed researchers to get a glimpse of the composition of the intestinal flora in dogs (Handl and others 2011, Suchodolski 2011). The results of those studies showed that the gut of healthy dogs is inhabited by bacteria from several hundred different genera, with an estimated load ranging between 10 12 and 10 14 microbial cells.…”

Section: An Unsolved Mysterymentioning

confidence: 99%

What is causing acute haemorrhagic diarrhoea syndrome in dogs?

Dunowska

2017

Veterinary Record

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Intestinal Microbiota of Dogs and Cats: a Bigger World than We Thought

Cited by 107 publications

References 45 publications

Dietary fibre and the importance of the gut microbiota in feline nutrition: a review

Dietary fibre and the importance of the gut microbiota in feline nutrition: a review

Association of Obesity with Serum Leptin, Adiponectin, and Serotonin and Gut Microflora in Beagle Dogs

What is causing acute haemorrhagic diarrhoea syndrome in dogs?

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