Intestinal Parasitic Infections among Diabetic Patients in Tertiary Care Hospital

Abstract

Background and Aims. This study was conducted to investigate intestinal parasitic infections among diabetes patients compared to nondiabetic (control) individuals and examine the intensity of parasitosis in both groups. Even though diabetes poses a risk for parasitic infections, similarly, few recent studies suggest that parasitic infections, especially toxoplasmosis, and cysticercosis affecting pancreatic cells, can cause a decrease in insulin secretion, thus leading to diabetes. A retrospective study was carried out to find intestinal parasite infections among diabetics and nondiabetics in tertiary care hospitals. The records were collected from Microbiology Laboratory for five years. Out of 625 patients included in the study, two hundred twenty-seven (36.7%) were diabetic. Of these, most of the intestinal infections were caused by Hookworm (26.58%), followed by Blastocystis hominis (23.2%), and Entamoeba histolytica (12.23%). The risk factors involved in increased intestinal parasitosis were HIV and anemia. The most common parasite isolated among HIV patients was Isospora belli (30.23%). In anemic patients, Hookworm (4.04%) was the most frequently isolated parasite. This study also highlights the risk factors for acquiring intestinal parasites in diabetic patients, especially among patients with other comorbidities such as HIV.

The spectrum of parasitic infections with emphasis on the clinico-epidemiological characteristics and risk factors among immunocompromised and immunocompetent patients at a university hospital in Northern India

“…Thus the immunosuppression mediated by these underlying comorbidities was explained by a study by Khanna et al . [ 28 ] validates the lack of an intact immune system to defend one’s body from the effect of parasitic infections. While the above-mentioned study demonstrated a high incidence of helminthic infection in diabetics,[ 28 ] in contrast, the diabetic patients in this study were more prone to intestinal parasitic infections by protozoans namely Giardia lamblia .…”

Enteric Protozoan Parasitosis and Associated Factors among Patients with and without Diabetes Mellitus in a Teaching Hospital in Ghana

“…Before the fltration process, 10% formalin is used as a fxative that preserves the integrity of cysts and trophozoites that might be present in the specimen. Te diethyl ether dissolves debris and the centrifugation process concentrates and sediments the enteric parasites for examination [38]. For diagnostics and detection rate, the modifed Ziehl-Neelsen staining method was able to detect more of the intestinal coccidian compared to formol-ether concentration targeting both the intestinal coccidian and other enteric protozoa and the least performed is the direct wet mount technique.…”

Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy

“…The impact of microbial flora in the human body has aroused extensive concern. It not only plays an important role in the intestine, which is widely studied nowadays, but also gradually functions in other organ systems (Champer et al, 2018;Khanna et al, 2022). Nowadays, researchers pay more and more attention to women's health, especially the vaginal microbiota, since the vagina has a huge microecosystem containing billions of species of microorganisms (Witkin and Forney, 2020).…”