Intestinal Polyposis Associated with Melanosis Oris

Melanosis oris with Poliosis

“…Polyps have also been recorded in the nose and bladder. 8 The median time for the first presentation of polyps is about 11-13 years of age, and by the age of 20 years approximately 50% will have experienced symptoms.…”

“…Polyps can occur without pigmentation, just as pigmentation can occur without symptoms or evidence of polyposis, but these cases may not belong to this syndrome. 8 Hyperpigmentations can even disappear during adolescence. Diagnosis is defined by the presence of histopathologically confirmed hamartomatous polyps and at least two of the following clinical criteria: family history, hyperpigmentation and polyps in the small bowel.…”

Síndrome de Peutz-Jeghers

“…En adultos, el prolapso de pólipos se ha reportado en 24% de los casos estudiados. 10,19 VIGILANCIA El seguimiento de los pacientes con síndrome de Peutz-Jeghers se debe realizar con regularidad (cada uno o dos años) mediante endoscopia superior y baja, así como estudio baritado del intestino delgado para la detección temprana y remoción de todos los pólipos accesibles del tracto gastrointestinal. Los pólipos en el estómago, duodeno y colon son más frecuentes de lo que se espera, ya que la mayoría de éstos son asintomáticos y se recomienda su resección endoscópica.…”

Peutz-Jeghers Syndrome

“…Most patients become symptomatic in the first or the second decade of life. Andrews [1] describes the occurrence of hematemesis soon after birth in patients in which the characteristic pigmentation has de veloped only at the age of 5. On the other hand, the first symptoms may also occur in aged patients [26], In one third of cases, the symptoms appear before the 10th birthday; in another third abdominal symptoms ap pear around the age of 20.…”