Intestinal Trematode Infections

Toledo, Rafael; Muñoz-Antolí, Carla; Esteban, J. Guillermo

doi:10.1007/978-1-4939-0915-5_7

Cited by 35 publications

(44 citation statements)

References 143 publications

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“…Notably, children experience the highest prevalences and intensities of infection in these areas with over 270 million preschool-age and over 600 million school-age children currently infected 2 . An important number of these infections are caused by intestinal trematodes with estimates reaching 40 million people infected and more than 10% of the world’s population at risk of infection 3 4 5 6 . Commonly, intestinal helminths cause chronic and debilitating diseases associated with diarrhea, abdominal pain, malabsorption syndrome, vitamin deficiencies, anemia, growth retardation and/or impaired cognitive function among other symptoms 2 7 8 9 .…”

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confidence: 99%

Interleukin-25 Induces Resistance Against Intestinal Trematodes

Muñoz-Antolí

Cortés

Santano

et al. 2016

Sci Rep

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Echinostoma caproni is an intestinal trematode that has been extensively used as an experimental model to investigate the factors determining the resistance to intestinal helminths or the development of chronic infections. ICR mice are permissive hosts for E. caproni in which chronic infections are developed, concomitantly with local Th1 responses, elevated levels of local IFN-γ, inflammation and antibody responses. However, mice develop partial resistance to homologous challenge infections after cure of a primary infection, which converts this subject into an adequate model for the study of the mechanisms generating resistance against intestinal helminths. The purpose of the present study was to compare the immune response induced in primary and secondary infections to elucidate the factors determining the different outcome of the infection in each type of infection. The results obtained indicate that susceptibility is determined by the lack of IL-25 expression in response to primary infection. In contrast, infection in an environment with elevated levels of IL-25, as occurs in challenge infection, results in a Th2 phenotype impairing parasite survival. This was confirmed by treatment of naïve mice with exogenous IL-25 and subsequent infection. Changes induced in goblet cell populations and mucin glycosylation could be implicated in resistance to infection.

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confidence: 99%

Interleukin-25 Induces Resistance Against Intestinal Trematodes

Muñoz-Antolí

Cortés

Santano

et al. 2016

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“…En lo referente a las aves domésticas, como las aves de traspatio que se tienen en viviendas cercanas al área de estudio, no se considera que este trematodo represente un problema ya que los hospederos intermediarios que pueden participar en su ciclo biológico no forman parte de la dieta de estas aves. Finalmente, tampoco se considera que la diseminación de este trematodo en el área represente un riesgo para la salud humana, dado que son muy pocos los miembros de la superfamilia Diplostomoidea que afectan a humanos y sólo se han reportado casos al respecto en Europa y en Asia (Toledo et al 2014;López-Hernández 2018).…”

Section: Discussionunclassified

“…El análisis de las muestras fecales se realizó a través del método directo y del método de flotación con una solución sobresaturada de azúcar (Figueroa-Hernández & Rodríguez-Zea 2007;Zajac & Conboy 2012). Se procedió a realizar la identificación de los huevos encontrados con base en sus características morfológicas, realizando la comparación con registros fotográficos incluidos en publicaciones de diversos autores (Basch et al 1973;Hong et al 1984;Chai et al 1990;Thienpont et al 2003;Krone 2007;Zajac & Conboy 2012;Bowman 2014;Toledo et al 2014;Taylor et al 2016;Globokar et al 2017).…”

Section: Materiales Y Métodosunclassified

Estudio coproparasitológico de helmintos gastrointestinales en zopilotes negros (Coragyps atratus) de Livingston, Izabal, Guatemala

Callejas-Martínez

2019

Ciencias Veterinarias

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El objetivo del estudio fue determinar la presencia de helmintos gastrointestinales, a través del análisis coproparasitológico, en zopilotes negros (Coragyps atratus) de un área de Livingston, Izabal, Guatemala. Se analizó un total de 32 muestras fecales de estas aves por medio del método directo y el de flotación, con una solución sobresaturada de azúcar. De las 32 muestras analizadas, 21 (65.6%) resultaron positivas a la presencia de huevos de helmintos gastrointestinales; de estas, 20 (95.2%) presentaron huevos de trematodos; 3 (14.3%) presentaron huevos de nematodos; en 1 (4.8%) se encontró huevos de un acantocéfalo. Los huevos de un trematodo, de la superfamilia Diplostomoidea, fueron los más comúnmente observados, detectándose en 20 (62.5%) de las 32 muestras analizadas. Además, se encontraron huevos de un trematodo de la familia Echinostomatidae; de nematodos del género Heterakis y de las familias Ascarididae y Trichostrongylidae, así como huevos de Acanthocephala. De acuerdo con lo detectado a través del análisis coproparasitológico, los zopilotes negros evaluados presentaron helmintos gastrointestinales, predominando una especie de trematodo de la superfamilia Diplostomoidea. Los hallazgos de esta investigación constituyen un primer acercamiento al conocimiento de la fauna helmintológica gastrointestinal de Coragyps atratus en Guatemala.

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“…Emerged cercariae freely swim and infect the second intermediate hosts, which may be several species of aquatic organisms such as snails, frogs, clams and fishes. Finally, the definite host (human and others animals) become infected after ingestion of the second intermediate host harbouring the encysted metacercariae where an adults worms mature and produce eggs that are released with the host’s feces [ 2 , 3 ]. They infect the gastrointestinal tract of humans.…”

Section: Introductionmentioning

confidence: 99%

“…Patients are usually asymptomatic. However, with heavy infections, the worms can produce catarrhal inflammation with mild ulceration and the patient may experience abdominal pain, anorexia, nausea, vomiting, diarrhea and weight loss [ 2 , 3 ]. Infection are associated with common sociocultural practices of eating raw or insufficiently cooked mollusks, fish, crustaceans, and amphibians, promiscuous defecation, and use of night soil (human excrement collected from latrines) for fertilization of fish ponds [ 2 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Human echinostomiasis: a case report

et al. 2018

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BackgroundEchinostomiasis is a food-borne infection caused by an intestinal trematodes belonging to the family Echinostomatidae. They infect the gastrointestinal tract of humans. Patients are usually asymptomatic. However, with heavy infections, the worms can produce catarrhal inflammation with mild ulceration and the patient may experience abdominal pain, anorexia, nausea, vomiting, diarrhea and weight loss. Infection are associated with common sociocultural practices of eating raw or insufficiently cooked mollusks and fish.Case presentationWe report a first case of echinostomiasis from Nepal in a 62 years old, hindu male who presented to Tribhuvan University Teaching Hospital, Kathmandu with a complaint of abdominal pain and distension with vomiting on and off for 3–4 months. He had history of consumption of insufficiently cooked fish and snail with alcohol. During endoscopy, an adult flat worm was seen with mild portal hypertensive gastropathy (McCormack’s classification) and erosive duodenopathy. The adult worm was identified as Echinostoma species based on its morphology and characteristic ova found on stool routine microscopic examination of the patient. Patient was treated with praziquantel 40 mg/kg (single dose) which is the drug of choice for Echinostoma species infection by which he got improved and on follow up stool examination after 2 weeks revealed no ova of Echinostoma species.ConclusionsThe patients having history of consumption of insufficiently cooked snail and fish with suggestive clinical features of echinostomiasis should be suspected by physicians and ova of Echinostoma species should be searched by trained microscopists. An epidemiological survey is required to know the exact burden of Echinostoma species infection in the place where people have habit of eating insufficiently cooked fish and snails, as it can be endemic in that community or geographical area.

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Intestinal Trematode Infections

Cited by 35 publications

References 143 publications

Interleukin-25 Induces Resistance Against Intestinal Trematodes

Interleukin-25 Induces Resistance Against Intestinal Trematodes

Estudio coproparasitológico de helmintos gastrointestinales en zopilotes negros (Coragyps atratus) de Livingston, Izabal, Guatemala

Human echinostomiasis: a case report

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