Intoxicación aguda grave por cafeína. A propósito de 2 casos con 2 cursos diferentes

Fernández-Miret, Borja; Ávila, S. Castaño; Moliner, Javier; Rementería, M. Iturbe; Barrasa, Helena; Lozano, E. Corral

doi:10.1016/j.medin.2012.07.006

Cited by 3 publications

(5 citation statements)

References 3 publications

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“…In contrast, high doses of caffeine can lead to many fatal health problems, which have been reported in various countries. 2,[6][7][8][9]12,15 Therefore, many organizations and countries are calling attention to the overconsumption of caffeine preparations. [16][17][18] However, there are still many countries, including Japan, where they can be easily purchased over the counter.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5] Several case reports and forensic reports on acute caffeine poisoning have already been published. [6][7][8][9][10] In patients with acute caffeine poisoning, blood caffeine concentration plays a major role in treatment strategy, which is difficult to measure in real time. In 2014, we reported the correlation between blood lactate concentration and blood caffeine concentration in acute caffeine poisoning.…”

Section: Introductionmentioning

confidence: 99%

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Urinary glucose and ketone bodies as indicators of acute caffeine poisoning

Morita

Tsuji

Amino

et al. 2020

Acute Medicine & Surgery

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In various countries, many fatal health problems have been reported due to high intake of caffeine-rich energy drinks, tablets, and powders. In patients with acute caffeine poisoning, determination of blood caffeine concentration is an important yet difficult task. We aimed to assess whether the presence of glucose and ketone bodies in urine reflected the blood caffeine concentration in patients with acute caffeine poisoning. Methods: From April 2010 to March 2018, 25 patients with an overdose of only caffeine-rich tablets were admitted to our hospital. Their clinical features were investigated. In addition, we investigated whether the glucose and ketone bodies in the urine reflected blood caffeine concentration in 23 patients who underwent the urine qualitative test at admission. Results: The majority of the patients were young healthy women, whose average caffeine ingestion was 15.6 AE 8.1 g. Initial urine examinations showed glucose in 60% (14/23) of patients and ketone bodies in 57% (13/23) of patients. Ketone bodies or glucose were found in 78% (18/23) of the patients. The correlation between blood caffeine concentration and urinary glucose was R = 0.625, blood caffeine concentration and ketone bodies was R = 0.596, and blood caffeine and both was R = 0.76. Conclusion: Urine qualitative test is effective for differential diagnosis and severity assessment of acute caffeine poisoning in patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Urinary glucose and ketone bodies as indicators of acute caffeine poisoning

Morita

Tsuji

Amino

et al. 2020

Acute Medicine & Surgery

View full text Add to dashboard Cite

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“…Decontamination using activated charcoal is considered essential by some authors and should be used in patients presenting within a reasonable time frame of around 1-2 hours [17,31,32,37,41,45].…”

Section: Pathophysiology and Clinical Presentationmentioning

confidence: 99%

“…The first case of caffeine toxicity we found in our review of the literature treated with hemoperfusion was by Zimmerman et al, in the 1980s [25]. Since then, many others have described the use of several dialysis techniques in the management of acute caffeine intoxication [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45]. In the reported cases the most common acid base disorder was metabolic acidosis with elevated lactic acid.…”

Section: Pathophysiology and Clinical Presentationmentioning

confidence: 99%

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Treatment of Lethal Caffeine Overdose with Haemodialysis: A Case Report and Review

Gahona

Bharadwaj

Shah

et al. 2022

The Journal of Critical Care Medicine

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Caffeine, chemically 1,3,7-trimethylxanthine, is the most widely consumed central nervous system stimulant in the world with pleiotropic effects on the cardiovascular, pulmonary, and renal systems. The advent of over the counter (OTC) caffeine formulations has opened the window for potential toxicity, either by inadvertent or intentional overdosing. We present the case of a patient who attempted suicide by caffeine overdose treated with emergent haemodialysis and a review of the literature.

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Sleep, Adenosine and Caffeine as Tools for The Early Diagnosis of Parkinson Disease

Salín-Pascual¹

2012

TOSLPJ

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The information that has developed regarding Parkinson's Disease (PD) allowed to understand that there is a period of this disease, perhaps at least a decade, in which the classical features of PD are not detected as such, however, there are evidence of a series of non-motor manifestations, among which are: anosmia, constipation, psychiatric disorders such as major depression, generalized anxiety, and rapid eye movement sleep behavior disorder (RBD). On the other hand the understanding of physiological mechanisms of sleep-wake cycle, have become remarkable tools to explore neurological and psychiatric disorders and complemented the information and treatments for those disorders. There is evidence that RBD can occur in half of people who will develop PD, about 10 year letter. The role of adenosine in sleep and caffeine intolerance is other aspects that are evident in the relation between PD and sleep. The detection of PD in early stages, may allow the implementation of the type of therapeutic strategies for neuroprotection. The general goal would be delay or reduce the clinical manifestations of PD in some patients.

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Intoxicación aguda grave por cafeína. A propósito de 2 casos con 2 cursos diferentes

Cited by 3 publications

References 3 publications

Urinary glucose and ketone bodies as indicators of acute caffeine poisoning

Urinary glucose and ketone bodies as indicators of acute caffeine poisoning

Treatment of Lethal Caffeine Overdose with Haemodialysis: A Case Report and Review

Sleep, Adenosine and Caffeine as Tools for The Early Diagnosis of Parkinson Disease

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