Intra-abdominal bronchogenic cyst: report of five cases

Choi, Kang Kook; Sung, Ji Youn; Kim, Jung Sun; Kim, Min Jung; Park, Hyojun; Choi, Dong Wook; Choi, Seong Ho; Heo, Jin Seok

doi:10.14701/kjhbps.2012.16.2.75

Cited by 10 publications

(7 citation statements)

References 7 publications

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“…After 2 months of cyst excision, the CA 19-9 level returned to normal (cutoff: 35 U/mL) [ 13 ]. Another case with increased serum CA 19-9 level (144.1 U/mL) was reported by Choi et al [ 14 ]. Besides, the CEA level was elevated at 3777 µg/L (cutoff: 5 µg/L) inside the cyst, but normal at 4.3 µg/L in the serum [ 6 ].…”

Section: Discussionmentioning

confidence: 91%

Ectopic bronchogenic cyst in the retroperitoneal region: a case report and literature review of adult patients

Yuan

Shu

et al. 2021

BMC Surg

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Background Bronchogenic cyst is congenital aberration of bronchopulmonary malformation, which is rarely encountered in the abdomen and retroperitoneum. We present a case report and literature review of retroperitoneal bronchogenic cyst. Case presentation A 53-year-old female presented to outpatient clinic for a routine checkup of lumbar intervertebral disc herniation. She received a contrast computed tomography scan of the abdomen which revealed a retroperitoneal cystic lesion below the left crura of diaphragm. Afterward, the patient underwent a laparoscopic excision of the cystic lesion and was discharged uneventfully at postoperative day 4. Histopathological findings confirmed the diagnosis of retroperitoneal bronchogenic cyst. Our literature review identified 55 adult cases in recent two decades. The average age at diagnosis was 43.2 (range 17–69) years. 44 (80%) cases had a retroperitoneal cyst on the left side, and 52 (94.5%) cases underwent curative excision through open or laparoscopic surgery. In the available follow up of cases, there was no recurrence after surgery. Conclusions Bronchogenic cyst is rare in the retroperitoneal region. It should be considered as one of the differential diagnoses of a retroperitoneal neoplasm.

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Section: Discussionmentioning

confidence: 91%

Ectopic bronchogenic cyst in the retroperitoneal region: a case report and literature review of adult patients

Yuan

Shu

et al. 2021

BMC Surg

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“…Bronchogenic cysts are congenital cysts caused by abnormal sprouting from the ventral foregut during fetal life from the 3 rd to 7 th weeks[ 1 ]. Bronchogenic cysts usually occur in the mediastinum or lung, but there are rare cases of ectopic bronchogenic cysts that develop in the abdominal cavity or retroperitoneum[ 2 , 3 ]. There are some reports of malignant transformation in bronchogenic cysts, but the mechanism of tumorigenesis and malignant transformation is still unknown[ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Intra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm harboring a GNAS mutation: A case report

Murakami¹,

Shimizu²,

Yamazaki³

et al. 2022

WJCC

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BACKGROUND Bronchogenic cysts are congenital cysts caused by abnormal sprouting from the ventral foregut during fetal life. They usually occur in the mediastinum or lung, but there are very rare cases of ectopic bronchogenic cysts that develop in the abdominal cavity. A unique intra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm that was producing carcinoembryonic antigen (CEA), harboring a GNAS mutation, is reported. The present case may contribute to clarifying the mechanism of tumorigenesis and malignant transformation of ectopic bronchogenic cysts. CASE SUMMARY In 2007, a man in his 50s was incidentally found to have an intra-abdominal cystic mass, 8 cm in diameter. Surgical resection was recommended, but he preferred to remain under observation. In 2020, his serum CEA level increased to 26.7 ng/mL, and abdominal computed tomography showed a 15 cm × 12 cm, multifocal, cystic mass located predominantly on the lesser curvature of the stomach. Since malignancy could not be ruled out, he finally underwent surgical resection. Histologically, the cystic wall was lined by ciliated columnar epithelium, accompanied by bronchial gland-like tissue, bronchial cartilage, and smooth muscle. Part of the cyst consisted of atypical columnar epithelium with an MIB-1 index of 5% and positive for CEA. Moreover, a GNAS mutation (p.R201C) was detected in the atypical epithelium, leading to a diagnosis of an ectopic bronchogenic cyst with a low-grade mucinous neoplasm. The patient is currently undergoing outpatient follow-up without recurrence. CONCLUSION An extremely rare case of an abdominal bronchogenic cyst with a low-grade mucinous neoplasm harboring a GNAS mutation was reported.

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“…Bronchogenic cysts are a rare developmental malformation, which are thought to arise from an abnormal budding of the primitive foregut during early embryologic development. 1 Although bronchogenic cysts are predominantly found in the posterior mediastinum and related to the lung, tracheobronchial tree, or esophagus, it is assumed that an abnormal budding of the tracheobronchial rudiment could migrate into the subdiaphragmatic locations through the pleuroperitoneal channel. Nevertheless, bronchogenic cysts in the retroperitoneum are extremely rare, which constitutes only 0.03% of all retroperitoneal neoplasms.…”

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“…Nevertheless, bronchogenic cysts in the retroperitoneum are extremely rare, which constitutes only 0.03% of all retroperitoneal neoplasms. 1 Intra-abdominal bronchogenic cysts are typically located in the left side to the midline and in the vicinity of the pancreas tail, spleen, and left adrenal gland. 2 Although they are usually discovered incidentally in the left upper quadrant of the abdomen, retroperitoneal bronchogenic cysts occasionally present with epigastric or back pain.…”

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An Incidental Pancreatic Mass in a Young Woman

2017

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Question: A 37-year-old woman was admitted owing to a pancreatic mass, which was incidentally found at chest computed tomography (CT) scan for the evaluation of pneumonia 3 months before admission. She was asymptomatic and her family history was unremarkable. She was not alcoholic and had no history of pancreatitis or abdominal surgery. A physical examination showed that the abdomen was soft and flat without tenderness on palpation. The initial routine laboratory test, including full blood count, urea, electrolytes, and liver function test, was within the normal limit. Serum biochemistry analysis showed amylase 45 U/L (normal, 0-100), lipase 18 U/L (normal, 7-60), and glucose 92 mg/dL (normal, 60-100). Tumor markers (carcinoembryonic antigen, carbohydrate antigen 19-9) were unavailable. CT images show a well-defined, 5-cm mass in the pancreas tail, which is homogeneously hyperdense (107 HU), relatively hypodense (111 HU), and isodense (111 HU) as compared with the pancreas parenchyma on unenhanced (Figure A), pancreatic phase (obtained at 45 seconds after injection of contrast agent; Figure B), and portal phase (85 seconds; Figure C) CT images, respectively. On coronal portal phase CT image (Figure D), an amorphic calcification is noted in the periphery of the mass. There was no dilatation of main pancreatic duct and common bile duct. Endoscopic ultrasound image (Figure E) depicts a well-defined mass with homogeneous low-level echogenicity in the pancreas tail. Given the CT and endoscopic ultrasound images, what is the most probable diagnosis in this case? See the Gastroenterology web site (www.gastrojournal.org) for more information on submitting your favorite image to Clinical Challenges and Images in GI.

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Intra-abdominal bronchogenic cyst: report of five cases

Cited by 10 publications

References 7 publications

Ectopic bronchogenic cyst in the retroperitoneal region: a case report and literature review of adult patients

Ectopic bronchogenic cyst in the retroperitoneal region: a case report and literature review of adult patients

Intra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm harboring a GNAS mutation: A case report

An Incidental Pancreatic Mass in a Young Woman

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