Application of the ratings of perceived exertion-clamp model to examine the effects of joint angle on the time course of torque and neuromuscular responses during a sustained, isometric forearm flexion to task failure. J Strength Cond Res 37(5): 1023-1033, 2023-The present study used the ratings of perceived exertion (RPE)-clamp model during a sustained, isometric forearm flexion task to failure to determine the effects of joint angle on torque and neuromuscular responses. Twelve college-aged women performed two 3-second maximal voluntary isometric contractions at elbow joint angles (EJ) of 75˚, 100˚, and 125˚before sustained, isometric, forearm flexions anchored to RPE 5 7 to task failure (defined as RPE . 7, or the torque was reduced to zero) at EJ 75 , EJ 100 , and EJ 125 . The amplitude (AMP) and frequency (MPF) of the electromyographic (EMG) and mechanomyographic (MMG) signals from the biceps brachii were recorded. Repeated-measures ANOVAs and post hoc comparisons were used to examine differences across time and between joint angles for torque and neuromuscular parameters. A p-value #0.05 was considered significant. For each joint angle, there was a decrease (p , 0.05) in torque across the sustained, isometric task. Collapsed across joint angle, there were decreases (p , 0.001, h 2 p 5 0.378) in EMG AMP from 30 to 100% time to task failure. No changes were observed, however, for the other neuromuscular responses. The subjects voluntarily reduced torque to maintain RPE 5 7 for each joint angle, and we hypothesize that RPE was maintained by afferent feedback from group III/IV motor neurons and corollary discharge (efferent copy of an internal signal that develops from central motor commands). The RPE-Clamp Model may be extended to athletes recovering from injury because a self-selected exercise intensity may be perceived as more enjoyable and promote adherence.