Intra-Arterial Angiolymphoid Hyperplasia with Eosinophilia: A Rare Case Report of Peripheral Medium Sized Muscular Artery Involvement

Amin, Ashima N; Umashankar, T; Dsouza, Chryselle Olive

doi:10.7860/jcdr/2015/13044.6327

Cited by 5 publications

(1 citation statement)

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“…Lymphocytes, histiocytes, eosinophils, mast cells, and plasma cells are scattered [57]. When the mixed inflammatory infiltrate predominates or obscures the vascular component, EH can be misdiagnosed as Kimura's disease, response to an arthropod bite, or cutaneous lymphoproliferative disorders, among others (Tables 4-6) [57][58][59][60][61][62][63]. The key to EH diagnosis in such cases is recognizing the vascular component of the lesion [57].…”

Section: When the Inflammatory Component Predominatesmentioning

confidence: 99%

Epithelioid Haemangioma of Bone: A Case Series and Comprehensive Literature Review Reappraising the Diagnostic Classification of All Epithelioid Vascular Neoplasms of Bone

Ramkumar¹

2021

Cureus

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Epithelioid vascular neoplasms of the bone are classified by the World Health Organization (WHO) into only two tiers: low-grade epithelioid hemangioma (EH) and a more malignant category including both epithelioid hemangioendothelioma and epithelioid angiosarcoma. The World Health Organization defines bone EH as a locally aggressive neoplasm with no connotation of benign or intermediate malignancy. We reviewed three cases of EH in our lab archives with the perspective of appraising their histomorphological approach toward diagnosis. Patients were in the age range of 15-25 years. The site of the neoplasms ranged from the carpal bones to the metatarsal bones. Histomorphological examination of the lesions showed a nodular growth pattern of a vascular neoplasm without demonstrable vessel origin. The vasoformative area increased from the center to the periphery, with prominent epithelioid morphology of the endothelial cells at the periphery and an associated inflammatory infiltrate comprising eosinophils, lymphocytes, and plasma cells. The growth pattern was diffuse, with extension into the deeper dermis of overlying skin.

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