Intra-articular gouty tophi of the knee: CT and MR imaging in 12 patients

Chen, Clement K. H.; Yeh, Lee Ren; Pan, Huay‐Ben; Yang, Chien-Fang; Lu, Yih-Chau; Wang, Jyh-Seng; Resnick, Donald

doi:10.1007/s002560050477

Cited by 99 publications

(53 citation statements)

References 7 publications

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“…This is not unusual as the appearance of tophaceous gout on an MRI is usually nonspecific. [6,9,10] Therefore, an open biopsy was deemed necessary to come to a definitive diagnosis. We chose this over needle biopsy to ensure that we got an adequate tissue for sampling.…”

Section: Discussionmentioning

confidence: 99%

Gouty Tophi Mimicking Synovial Sarcoma of the Knee Joint

2012

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Section: Discussionmentioning

confidence: 99%

Gouty Tophi Mimicking Synovial Sarcoma of the Knee Joint

2012

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“…Since the MRI findings of tophaceous gout are non-specific, tophi mimic a tumor or an infection on MR images. Intra-articular tophi have been detected by intermediate to low signal intensity on T1 weighted MR images and various intensities on T2 weighted MR images 4,5) . In the present case, a diffuse mass in the pos- terior compartment of the knee was detected as low intensity on T1 weighted MR images and high intensity on T2 weighted MR images.…”

Section: Discussionmentioning

confidence: 99%

Gouty Synovitis of the Knee with Partial Hypoxanthine-guanine Phosphoribosyl Transferase Deficiency (Kelley-Seegmiller Syndrome): A Case Report

et al. 2009

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We present here a case of gouty synovitis of the knee in a patient with partial hypoxanthine-guanine phosphoribosyl transferase deficiency (Kelley-Seegmiller syndrome), which is an inherited purine metabolic disorder. Magnetic resonance images and computed tomography showed a diffuse mass with stippled calcification around the posterior cruciate ligament (PCL) in the posterior intercondylar notch. Arthroscopic examination revealed that the articular surfaces and menisci in the affected knee were almost completely covered with white chalky monosodium urate (MSU) crystals. The diffuse mass around the PCL was composed of proliferative synovial villi covered with MSU crystals that looked like "snow covered trees". Arthroscopic total synovectomy was performed. The posterior trans-septal portal was especially useful for removal of the proliferative villi around the PCL. To our knowledge, this is the first report of arthroscopic examination in a patient with Kelley-Seegmiller syndrome.

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“…These features relate primarily to internal calcifications, which are most evident on CT scans. Magnetic resonance imaging scan (including Gd administration) supplemented, in some cases, with CT scan allows accurate diagnosis of intraarticular tophaceous deposits [9]. Monosodium urate (MSU) deposits within a tophus can be clearly defined with CT scan.…”

Section: Ozkan Et Al 595mentioning

confidence: 99%

“…Photomicrograph of another section had been stained by de Galantha's method for demonstration of monosodium urate crystals ( Figure 2). subcutaneous nodules, knee, acromioclavicular joint and axial skeleton [3][4][5][6][7][8][9][10][11][12][13][14]. A recent study suggested that the frequency of axial involvement may be as high as 14% in patients with clinical or crystal-proven gout [15].…”

Section: Case Reportmentioning

confidence: 99%

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Tophi gout around the knee joint: An unusual presentation with a soft tissue mass

Özkan¹,

Bilsel²,

Türkmen³

et al. 2013

IJCRI

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Introduction: Gout is the most common inflammatory arthropathy. It has been reported to affect 2.13% of population in the United states. In this report, we presented an uncommon case of tophaceous gout of the knee presenting as a soft tissue mass. case report: A 57-year-old male patient with knee pain and localized progressive swelling increasing in time on the medial side of the proximal tibia was seen in our clinic. He did not have any rheumatologic disease known previously except gout arthritis. Excisional biopsy was performed by preserving medial collateral ligament and histopathologic investigations were done next. A tophaceous gouty deposit was identified by low-power photomicrograph. A bluish amorphous material was seen surrounded by bundles of dense collagenized tissue and chronic inflammatory cells. surrounding the amorphous crystalline deposit is a thin layer of mononuclear and giant cells. Photomicrograph of another section has been stained by de Galantha's method for demonstration of monosodium urate crystals. conclusion: Especially in patients with extra-articular or subcutaneus mass, tophaceous gout must be considered as differential diagnosis.

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Intra-articular gouty tophi of the knee: CT and MR imaging in 12 patients

Cited by 99 publications

References 7 publications

Gouty Tophi Mimicking Synovial Sarcoma of the Knee Joint

Gouty Tophi Mimicking Synovial Sarcoma of the Knee Joint

Gouty Synovitis of the Knee with Partial Hypoxanthine-guanine Phosphoribosyl Transferase Deficiency (Kelley-Seegmiller Syndrome): A Case Report

Tophi gout around the knee joint: An unusual presentation with a soft tissue mass

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