Intra-Cranial Lesions in a Patient with Hodgkin Lymphoma

Abstract

Central nervous system (CNS) lesions in newly diagnosed, advanced Hodgkin's disease (HD) commonly suggest intracranial involvement with HD. However, occasionally this could be the result of a CNS infection. We report a case of concurrent CNS tuberculosis in a patient with stage III E HD the first reported in the English literature. Management of this case and the literature pertaining to infectious complications of HD are reviewed.

Central nervous system involvement in Hodgkin's lymphoma associated with Epstein-Barr virus in a patient with AIDS: case report and review of the literature

“…Finally, unusual and aggressive extranodal presentations of HL should alert to the possibility of HIV infection. Whole brain irradiation and systemic chemotherapy remain the treatment of choice for CNS involvement in patients with HL [5,16,17].…”

Mantle cell lymphoma involvement of the pleura and tuberculous pleurisy with pulmonary tuberculosis: a case report and literature review

“…Keywords used in various combinations were ''tuberculosis,'' ''lymphoma,'' ''co-existence,'' and ''concurrently.'' Including our present case, 17 cases were reported (Table 2) [11][12][13][14][15][16][17][18][19][20][21][22][23][24]. Fourteen of the 17 cases were pulmonary tuberculosis or lymph node tuberculosis.…”

Pulmonary mycobacteriosis in a patient affected by mycosis fungoides: A diagnostic and therapeutic challenge

“…tuberculosis, 18 was described to date only in one patient, whereas this association has been reported in several cases of Hodgkin's and non-Hodgkin's lymphoma. 19,20 In our patient both the lymphoma and its treatment contributed to immunosuppression and may have predisposed to the development of pulmonary mycobacteriosis. 8,18,22 With regard to the diagnosis of lung infection, the first diagnosis proposed by radiologists was a post-radiotherapy process.…”